Interspecies Spread of Klebsiella pneumoniae Carbapenemase Gene in a Single Patient

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae, Escherichia coli, and Serratia marcescens were sequentially identified in a patient who underwent small bowel transplantation. Molecular typing and plasmid analysis suggested that the KPC gene was acquired by E. coli, most likely fro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical infectious diseases 2009-12, Vol.49 (11), p.1736-1738
Hauptverfasser:	Sidjabat, Hanna E., Silveira, Fernanda P., Potoski, Brian A., Abu-Elmagd, Kareem M., Adams-Haduch, Jennifer M., Paterson, David L., Doi, Yohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Bacterial Agents - therapeutic use Antibiotics Bacteremia Bacterial Proteins - genetics beta-Lactamases - genetics Biological and medical sciences BRIEF REPORTS Carbapenems Carbapenems - therapeutic use Drug Resistance, Bacterial - genetics E coli Enterobacteriaceae Escherichia coli Escherichia coli - genetics Female Gene Transfer, Horizontal - genetics Genes Humans Infectious diseases Klebsiella Infections - drug therapy Klebsiella Infections - microbiology Klebsiella pneumoniae Klebsiella pneumoniae - enzymology Klebsiella pneumoniae - genetics Medical sciences Plasmids Plasmids - genetics Polymerase Chain Reaction Serratia marcescens Serratia marcescens - genetics Transplants & implants Transposons
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae, Escherichia coli, and Serratia marcescens were sequentially identified in a patient who underwent small bowel transplantation. Molecular typing and plasmid analysis suggested that the KPC gene was acquired by E. coli, most likely from K. pneumoniae, and was subsequently transferred to S. marcescens .
ISSN:	1058-4838 1537-6591
DOI:	10.1086/648077