Synthesis and biological evaluation of 3′,4′,5′-trimethoxychalcone analogues as inhibitors of nitric oxide production and tumor cell proliferation

A series of 23 3′,4′,5′-trimethoxychalcone analogues were synthesized and their inhibitory effects, on nitric oxide production in LPS/IFN-γ-treated macrophages, and human tumor cell proliferation has been investigated. A series of 23 3′,4′,5′-trimethoxychalcone analogues was synthesized and their in...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2009-12, Vol.17 (23), p.7909-7914
Hauptverfasser: Rao, Yerra Koteswara, Fang, Shih-Hua, Tzeng, Yew-Min
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Sprache:eng
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