Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of medicinal chemistry 1992-11, Vol.35 (24), p.4640-4642
Hauptverfasser:	Hartman, George D, Egbertson, Melissa S, Halczenko, Wasyl, Laswell, William L, Duggan, Mark E, Smith, Robert L, Naylor, Adel M, Manno, Patricia D, Lynch, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - pharmacology Amino Acid Sequence Binding Sites Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Fibrinogen - metabolism Humans Molecular Sequence Data Molecular Structure Oligopeptides - pharmacology Platelet Aggregation Inhibitors - chemical synthesis Platelet Aggregation Inhibitors - pharmacology Platelet Membrane Glycoproteins - antagonists & inhibitors Platelet Membrane Glycoproteins - metabolism Tirofiban Tyrosine - analogs & derivatives Tyrosine - chemical synthesis Tyrosine - pharmacology Umbilical Veins
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