MAP-ping Unconventional Protein-DNA Interactions

MAP-ping Unconventional Protein-DNA Interactions

Control of gene expression depends on a myriad of protein-DNA interactions, and the number of proteins involved just got larger. In this issue, Hu et al. (2009) identify hundreds of human proteins that bind to DNA, including many surprises such as the protein kinase ERK2 (MAPK1) that now appears to...

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Veröffentlicht in:Cell 2009-10, Vol.139 (3), p.462-463
Hauptverfasser: Dioum, Elhadji M., Wauson, Eric M., Cobb, Melanie H.
Format: Artikel
Sprache:eng
Schlagworte:
DNA - metabolism
DNA-Binding Proteins - metabolism
Gene Expression Regulation
Humans
Mitogen-Activated Protein Kinase 1 - metabolism
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Zusammenfassung:Control of gene expression depends on a myriad of protein-DNA interactions, and the number of proteins involved just got larger. In this issue, Hu et al. (2009) identify hundreds of human proteins that bind to DNA, including many surprises such as the protein kinase ERK2 (MAPK1) that now appears to control gene expression directly.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2009.10.007