efficient protocol for the synthesis of 2-amino-4,6-diphenylpyridine-3-carbonitrile using ionic liquid ethylammonium nitrate

Chalcones on condensation with malononitrile and ammonium acetate in the presence of ionic liquid ethylammonium nitrate affords the corresponding 2-amino-4, 6-diphenylpyridine-3-carbonitrile in excellent yield. The ionic liquid is recycled and reused several times.

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Veröffentlicht in:Molecular diversity 2009-11, Vol.13 (4), p.545-549
Hauptverfasser: Sarda, Swapnil R, Kale, Jagpal D, Wasmatkar, Sunil K, Kadam, Vijay S, Ingole, Pravin G, Jadhav, Wamanrao N, Pawar, Rajendra P
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Sprache:eng
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Zusammenfassung:Chalcones on condensation with malononitrile and ammonium acetate in the presence of ionic liquid ethylammonium nitrate affords the corresponding 2-amino-4, 6-diphenylpyridine-3-carbonitrile in excellent yield. The ionic liquid is recycled and reused several times.
ISSN:1381-1991
1573-501X
DOI:10.1007/s11030-009-9132-1