Synthesis of Phthalocyanines−ALA Conjugates: Water-Soluble Compounds with Low Aggregation

Syntheses of two water-soluble phthalocyanines (Pc) containing 5-aminolevulinic acid (ALA) linked to the core structure are described. These compounds were prepared by using original functionalizations, and they present remarkable structural and photophysical features, indicating that they could be...

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Veröffentlicht in:	Journal of organic chemistry 2009-10, Vol.74 (20), p.7962-7965
Hauptverfasser:	de Oliveira, Kleber T, de Assis, Francisco F, Ribeiro, Anderson O, Neri, Claudio R, Fernandes, Adjaci U, Baptista, Mauricio S, Lopes, Norberto P, Serra, Osvaldo A, Iamamoto, Yassuko
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminolevulinic Acid - chemical synthesis Aminolevulinic Acid - chemistry Indoles - chemical synthesis Indoles - chemistry Molecular Structure Solubility Water - chemistry
Online-Zugang:	Volltext
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Zusammenfassung:	Syntheses of two water-soluble phthalocyanines (Pc) containing 5-aminolevulinic acid (ALA) linked to the core structure are described. These compounds were prepared by using original functionalizations, and they present remarkable structural and photophysical features, indicating that they could be applied to photodynamic therapy (PDT).
ISSN:	0022-3263 1520-6904
DOI:	10.1021/jo901633a