Do Substantia Nigra Dopaminergic Neurons Differentiate Between Reward and Punishment?

The activity of dopaminergic neurons are thought to be increased by stimuli that predict reward and decreased by stimuli that predict aversive outcomes. Recent work by Matsumoto and Hikosaka challenges this model by asserting that stimuli associated with either rewarding or aversive outcomes increas...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of molecular cell biology 2009-10, Vol.1 (1), p.15-16
Hauptverfasser:	Frank, Michael J., Surmeier, D. James
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Conditioning (Psychology) - physiology Dopamine - metabolism Haplorhini - physiology Neurons - physiology Punishment Rats Reward Substantia Nigra - physiology
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The activity of dopaminergic neurons are thought to be increased by stimuli that predict reward and decreased by stimuli that predict aversive outcomes. Recent work by Matsumoto and Hikosaka challenges this model by asserting that stimuli associated with either rewarding or aversive outcomes increase the activity of dopaminergic neurons in the substantia nigra pars compacta.
ISSN:	1674-2788 1759-4685
DOI:	10.1093/jmcb/mjp010