Can Cinacalcet Replace Parathyroid Intervention in Severe Secondary Hyperparathyroidism?

A 6‐month observational study was conducted in 61 patients (33 men and 28 women, mean age 54.8 ± 12.4 years) treated with cinacalcet in whom parathyroid intervention was indicated. Thirty‐seven patients had baseline intact parathyroid hormone (iPTH) levels of >500 pg/mL, but only five still had levels this high after 6‐month cinacalcet therapy. No patients had phosphorus (P), calcium (Ca), or iPTH levels within the target range at baseline, but six patients (9.8%) reached all three target ranges after treatment. The stratum with many patients who had 2–4 enlarged parathyroid glands shifted toward the low PTH groups (iPTH