Shape and Release Control of a Peptide Decorated Vesicle through pH Sensitive Orthogonal Supramolecular Interactions

A pH sensitive carrier is obtained by coating a cyclodextrin vesicle with an adamantane-terminated octapeptide through the formation of an inclusion complex. Upon lowering the pH from 7.4 to 5.0, the formation of peptide β-sheets on the vesicle surface induces a transition of the bilayer from a sphe...

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Veröffentlicht in:	Journal of the American Chemical Society 2009-09, Vol.131 (37), p.13186-13187
Hauptverfasser:	Versluis, Frank, Tomatsu, Itsuro, Kehr, Seda, Fregonese, Carlo, Tepper, Armand W.J.W, Stuart, Marc C. A, Ravoo, Bart Jan, Koning, Roman I, Kros, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Circular Dichroism Cyclodextrins - chemistry Fluorescent Dyes - chemistry Hydrogen-Ion Concentration Membranes, Artificial Oligopeptides - chemistry Protein Structure, Secondary Surface Properties
Online-Zugang:	Volltext
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