Use of Misoprostol for Management of Unsatisfactory Colposcopy in the Adolescent: A Case Report and Review of the Literature

Abstract Study Objective To document the ability to use a prostaglandin analogue to achieve satisfactory colposcopy in a patient with cervical stenosis and unsatisfactory colposcopy. Design Case report. Results Satisfactory colposcopy was achieved by using 100 mg of Misoprostol orally, administered the night before the planned colposcopic evaluation. Conclusion In the presence of persistent atypia in an adolescent female with an unsatisfactory colposcopy, consider using a prostaglandin analogue for adequate evaluation of the endocervix, prior to proceeding with an ablative or excisional therapy.