Effect of Dietary Astaxanthin at Different Stages of Mammary Tumor Initiation in BALB/c Mice

The effects of astaxanthin on tumor growth, cardiac function and immune response in mice were studied. Female BALB/c mice were fed a control diet (diet C) for 8 weeks, 0.005% astaxathin for 8 weeks (diet A), or diet C for weeks 1-5 followed by diet A thereafter (diet CA). Mice were injected with a m...

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Veröffentlicht in:	Anticancer research 2010-06, Vol.30 (6), p.2171-2175
Hauptverfasser:	NAKAO, Ruriko, NELSON, O. Lynne, JEAN SOON PARK, MATHISON, Bridget D, THOMPSON, Pam A, CHEW, Boon P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Female Glutathione - metabolism Interferon-gamma - biosynthesis Mammary Neoplasms, Experimental - immunology Mammary Neoplasms, Experimental - pathology Mammary Neoplasms, Experimental - prevention & control Medical sciences Mice Mice, Inbred BALB C Neoplasm Staging Serum Amyloid A Protein - analysis Tumor Necrosis Factor-alpha - blood Tumors Ventricular Function, Left Xanthophylls - administration & dosage
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Zusammenfassung:	The effects of astaxanthin on tumor growth, cardiac function and immune response in mice were studied. Female BALB/c mice were fed a control diet (diet C) for 8 weeks, 0.005% astaxathin for 8 weeks (diet A), or diet C for weeks 1-5 followed by diet A thereafter (diet CA). Mice were injected with a mammary tumor cell line on day 7 and tumor growth was measured daily. Mice fed diet A had extended tumor latency and lower tumor volume (p
ISSN:	0250-7005 1791-7530