l-Histidine and l-arginine promote Knoevenagel reaction in water
Histidine and arginine were applied to the synthesis of trisubstituted alkenes through a condensation of an aldehyde with an activated CH-acid such as ethyl cyanoacetate, malononitrile, acetyl acetone or ethyl acetoacetate during 5-12 h in water at room temperature.
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Veröffentlicht in: | Amino acids 2010-08, Vol.39 (3), p.911-916 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Histidine and arginine were applied to the synthesis of trisubstituted alkenes through a condensation of an aldehyde with an activated CH-acid such as ethyl cyanoacetate, malononitrile, acetyl acetone or ethyl acetoacetate during 5-12 h in water at room temperature. |
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ISSN: | 0939-4451 1438-2199 |
DOI: | 10.1007/s00726-010-0537-z |