Development of Bronchiolitis Obliterans Organizing Pneumonia With Platinum-Based Chemotherapy for Metastatic Rectal Cancer

Abstract Bronchiolitis obliterans organizing pneumonia (BOOP) is an adverse event known to occur after cancer chemotherapy and radiotherapy. We present a case of a 47-year-old patient who was diagnosed with BOOP after treatment for metastatic rectal cancer with oxaliplatin/capecitabine/bevacizumab....

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Veröffentlicht in:	Clinical colorectal cancer 2010-07, Vol.9 (3), p.177-178
Hauptverfasser:	Fekrazad, M. Houman, Eberhardt, Steve, Jones, Dennie V, Lee, Fa-Chyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal, Humanized Antineoplastic Agents - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bevacizumab BOOP Capecitabine Cryptogenic Organizing Pneumonia - chemically induced Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Fluorouracil - administration & dosage Fluorouracil - analogs & derivatives Gastroenterology and Hepatology Hematology, Oncology and Palliative Medicine Humans Irinotecan Male Middle Aged Organoplatinum Compounds - adverse effects Oxaliplatin Pulmonary disease Rectal Neoplasms - drug therapy
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Zusammenfassung:	Abstract Bronchiolitis obliterans organizing pneumonia (BOOP) is an adverse event known to occur after cancer chemotherapy and radiotherapy. We present a case of a 47-year-old patient who was diagnosed with BOOP after treatment for metastatic rectal cancer with oxaliplatin/capecitabine/bevacizumab. Removal of oxaliplatin from the regimen and replacement with irinotecan resulted in a resolution of his pulmonary symptoms.
ISSN:	1533-0028 1938-0674
DOI:	10.3816/CCC.2010.n.024