Fabrication of Gold Nanoparticles Inside Unmodified Horse Spleen Apoferritin

Size‐constrained gold nanoparticles are successfully synthesized within the cavity of native horse spleen ferritin by using a two‐step process relying on the initial formation of nanoclusters. The particles co‐elute with the nanocage ferritin by chromatography, indicating that the particles are asso...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2010-07, Vol.6 (14), p.1483-1487
Hauptverfasser:	Fan, Rongli, Chew, Shu Wen, Cheong, Vee Vee, Orner, Brendan Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoferritins - chemistry biomineralization Chromatography, Gel encapsulation gold Gold - chemistry Horses Microscopy, Electron, Transmission nanomaterials Nanoparticles proteins Spectrophotometry, Ultraviolet Spleen - chemistry Surface Plasmon Resonance
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Beschreibung
Zusammenfassung:	Size‐constrained gold nanoparticles are successfully synthesized within the cavity of native horse spleen ferritin by using a two‐step process relying on the initial formation of nanoclusters. The particles co‐elute with the nanocage ferritin by chromatography, indicating that the particles are associated with intact protein cages. Further characterization reveals that the growth of the monodisperse particles is limited by the protein cage.
ISSN:	1613-6810 1613-6829
DOI:	10.1002/smll.201000457