Stabilized liposomal nanohybrid cerasomes for drug delivery applications

Paclitaxel loaded cerasomes exhibited sophisticated controlled release behavior and remarkably high stability towards surfactant solubilization, long-term storage, acidic treatment, and all factors susceptible to destabilize conventional liposomes, demonstrating that liposomal nanohybrid cerasomes c...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2010-08, Vol.46 (29), p.5265-5267
Hauptverfasser:	Cao, Zhong, Ma, Yan, Yue, Xiuli, Li, Shouzhu, Dai, Zhifei, Kikuchi, Junichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Proliferation - drug effects Drug Delivery Systems Humans Liposomes - chemistry Microscopy, Electron, Scanning Molecular Structure Nanostructures - administration & dosage Nanostructures - chemistry Nanostructures - ultrastructure Paclitaxel - administration & dosage Paclitaxel - chemistry
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Beschreibung
Zusammenfassung:	Paclitaxel loaded cerasomes exhibited sophisticated controlled release behavior and remarkably high stability towards surfactant solubilization, long-term storage, acidic treatment, and all factors susceptible to destabilize conventional liposomes, demonstrating that liposomal nanohybrid cerasomes can be a new promising drug delivery system.
ISSN:	1364-548X
DOI:	10.1039/b926367e