Antioxidant status in the aqueous humour of patients with glaucoma associated with exfoliation syndrome
Purpose To establish the antioxidant status of the aqueous humour in glaucoma associated with exfoliation syndrome (XFG) and to compare it to primary open-angle glaucoma (POAG) and cataract patients. Methods Patients were diagnosed with POAG, XFG, or cataract ( n =25 for each group). Total reactive...
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Veröffentlicht in: | Eye (London) 2009-08, Vol.23 (8), p.1691-1697 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Purpose
To establish the antioxidant status of the aqueous humour in glaucoma associated with exfoliation syndrome (XFG) and to compare it to primary open-angle glaucoma (POAG) and cataract patients.
Methods
Patients were diagnosed with POAG, XFG, or cataract (
n
=25 for each group). Total reactive antioxidant potential (TRAP) was measured by chemiluminescence. Ascorbic acid levels and the activities of catalase, glutathione peroxidase (GPx), and superoxide dismutase (SOD) were measured spectrophotometrically.
Results
TRAP value was lower in XFG (28±2
μ
M Trolox) than in POAG (55±8
μ
M Trolox;
P |
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ISSN: | 0950-222X 1476-5454 |
DOI: | 10.1038/eye.2008.352 |