Antioxidant status in the aqueous humour of patients with glaucoma associated with exfoliation syndrome

Purpose To establish the antioxidant status of the aqueous humour in glaucoma associated with exfoliation syndrome (XFG) and to compare it to primary open-angle glaucoma (POAG) and cataract patients. Methods Patients were diagnosed with POAG, XFG, or cataract ( n =25 for each group). Total reactive...

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Veröffentlicht in:Eye (London) 2009-08, Vol.23 (8), p.1691-1697
Hauptverfasser: Ferreira, S M, Lerner, S F, Brunzini, R, Evelson, P A, Llesuy, S F
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Sprache:eng
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Zusammenfassung:Purpose To establish the antioxidant status of the aqueous humour in glaucoma associated with exfoliation syndrome (XFG) and to compare it to primary open-angle glaucoma (POAG) and cataract patients. Methods Patients were diagnosed with POAG, XFG, or cataract ( n =25 for each group). Total reactive antioxidant potential (TRAP) was measured by chemiluminescence. Ascorbic acid levels and the activities of catalase, glutathione peroxidase (GPx), and superoxide dismutase (SOD) were measured spectrophotometrically. Results TRAP value was lower in XFG (28±2  μ M Trolox) than in POAG (55±8  μ M Trolox; P
ISSN:0950-222X
1476-5454
DOI:10.1038/eye.2008.352