Autologous Transplantation of Bone Marrow Mononuclear Cells Improved Ischemic Peripheral Neuropathy in Humans
[...]we examined whether autologous transplantation of BM-MNCs would improve ischemic neuropathy with critical limb ischemia in humans. Furthermore, BM-MNC transplantation improved objective peripheral nerve functions (MNCV, CMAP, and QVT) in the treated limb but not in the control limb, suggesting...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2010-07, Vol.56 (3), p.238-239 |
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| container_title | Journal of the American College of Cardiology |
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| creator | Arima, Ken, MD Katsuda, Yousuke, MD, PhD Takeshita, Yoshiaki, MD, PhD Saito, Yutaka, MD, PhD Toyama, Yasuyuki, MD Katsuki, Yoshio, MD Ootsuka, Masanori, MD Koiwaya, Hiroshi, MD Sasaki, Ken-ichiro, MD, PhD Kai, Hisashi, MD, PhD Imaizumi, Tsutomu, MD, PhD |
| description | [...]we examined whether autologous transplantation of BM-MNCs would improve ischemic neuropathy with critical limb ischemia in humans. Furthermore, BM-MNC transplantation improved objective peripheral nerve functions (MNCV, CMAP, and QVT) in the treated limb but not in the control limb, suggesting that the effects were not related to natural course or nonspecific effects. [...]autologous BM-MNC transplantation might improve not only peripheral blood perfusion but also ischemic peripheral neuropathy. |
| doi_str_mv | 10.1016/j.jacc.2010.02.050 |
| format | Article |
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Vascular system ; Cardiovascular ; Humans ; Internal Medicine ; Ischemia ; Medical imaging ; Medical sciences ; Middle Aged ; Pain ; Peripheral Nervous System Diseases - surgery ; Transplantation, Autologous ; Transplants & implants ; Vascular endothelial growth factor</subject><ispartof>Journal of the American College of Cardiology, 2010-07, Vol.56 (3), p.238-239</ispartof><rights>American College of Cardiology Foundation</rights><rights>2010 American College of Cardiology Foundation</rights><rights>2015 INIST-CNRS</rights><rights>Copyright Elsevier Limited Jul 13, 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c529t-3ba020255da96f449baac6082009e42cc4d0f1b33b02bc2a4ad34d68b920aee3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jacc.2010.02.050$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23038817$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20620746$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arima, Ken, MD</creatorcontrib><creatorcontrib>Katsuda, Yousuke, MD, PhD</creatorcontrib><creatorcontrib>Takeshita, Yoshiaki, MD, PhD</creatorcontrib><creatorcontrib>Saito, Yutaka, MD, PhD</creatorcontrib><creatorcontrib>Toyama, Yasuyuki, MD</creatorcontrib><creatorcontrib>Katsuki, Yoshio, MD</creatorcontrib><creatorcontrib>Ootsuka, Masanori, MD</creatorcontrib><creatorcontrib>Koiwaya, Hiroshi, MD</creatorcontrib><creatorcontrib>Sasaki, Ken-ichiro, MD, PhD</creatorcontrib><creatorcontrib>Kai, Hisashi, MD, PhD</creatorcontrib><creatorcontrib>Imaizumi, Tsutomu, MD, PhD</creatorcontrib><title>Autologous Transplantation of Bone Marrow Mononuclear Cells Improved Ischemic Peripheral Neuropathy in Humans</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>[...]we examined whether autologous transplantation of BM-MNCs would improve ischemic neuropathy with critical limb ischemia in humans. Furthermore, BM-MNC transplantation improved objective peripheral nerve functions (MNCV, CMAP, and QVT) in the treated limb but not in the control limb, suggesting that the effects were not related to natural course or nonspecific effects. [...]autologous BM-MNC transplantation might improve not only peripheral blood perfusion but also ischemic peripheral neuropathy.</description><subject>Angiogenesis</subject><subject>Arterial Occlusive Diseases - complications</subject><subject>Biological and medical sciences</subject><subject>Bone marrow</subject><subject>Bone Marrow Transplantation</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Ischemia</subject><subject>Medical imaging</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pain</subject><subject>Peripheral Nervous System Diseases - surgery</subject><subject>Transplantation, Autologous</subject><subject>Transplants & implants</subject><subject>Vascular endothelial growth factor</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Ul2LFDEQDKJ46-gf8EECIj7N2knmE0Q4F_UW7lRw30Mm0-NmnUnmkpmT_fdm2NWDe5A8NISq7uqqJuQlgzUDVrw7rA9K6zWH-AF8DTk8IiuW51Uq8rp8TFZQijxlUJcX5FkIBwAoKlY_JRccCg5lVqzIcDlPrnc_3Rzozisbxl7ZSU3GWeo6-tFZpDfKe_eb3jjr7Kx7VJ5usO8D3Q6jd3fY0m3QexyMpt_Rm3GPXvX0K87ejWraH6mx9GoeYvPn5Emn-oAvzjUhu8-fdpur9Prbl-3m8jrVOa-nVDQKOPA8b1VddFlWN0rpAioOUGPGtc5a6FgjRAO80VxlqhVZW1RNzUEhioS8PbWN8m5nDJMcTNBRsrIYF5WlEHUhsvgS8voB8uBmb6M2yfJoUgksghPCTyjtXQgeOzl6Myh_lAzkEoU8yCUKuUQhgcsYRSS9OreemwHbf5S_3kfAmzNABa36LrqvTbjHCRBVFccn5P0Jh9GxO4NeBm3QamyNRz3J1pn_6_jwgK57Y02c-AuPGO73lSES5I_laJabYRB3h6IUfwAP5Lxh</recordid><startdate>20100713</startdate><enddate>20100713</enddate><creator>Arima, Ken, MD</creator><creator>Katsuda, Yousuke, MD, PhD</creator><creator>Takeshita, Yoshiaki, MD, PhD</creator><creator>Saito, Yutaka, MD, PhD</creator><creator>Toyama, Yasuyuki, MD</creator><creator>Katsuki, Yoshio, MD</creator><creator>Ootsuka, Masanori, MD</creator><creator>Koiwaya, Hiroshi, MD</creator><creator>Sasaki, Ken-ichiro, MD, PhD</creator><creator>Kai, Hisashi, MD, PhD</creator><creator>Imaizumi, Tsutomu, MD, PhD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20100713</creationdate><title>Autologous Transplantation of Bone Marrow Mononuclear Cells Improved Ischemic Peripheral Neuropathy in Humans</title><author>Arima, Ken, MD ; Katsuda, Yousuke, MD, PhD ; Takeshita, Yoshiaki, MD, PhD ; Saito, Yutaka, MD, PhD ; Toyama, Yasuyuki, MD ; Katsuki, Yoshio, MD ; Ootsuka, Masanori, MD ; Koiwaya, Hiroshi, MD ; Sasaki, Ken-ichiro, MD, PhD ; Kai, Hisashi, MD, PhD ; Imaizumi, Tsutomu, MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c529t-3ba020255da96f449baac6082009e42cc4d0f1b33b02bc2a4ad34d68b920aee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Angiogenesis</topic><topic>Arterial Occlusive Diseases - complications</topic><topic>Biological and medical sciences</topic><topic>Bone marrow</topic><topic>Bone Marrow Transplantation</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Ischemia</topic><topic>Medical imaging</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pain</topic><topic>Peripheral Nervous System Diseases - surgery</topic><topic>Transplantation, Autologous</topic><topic>Transplants & implants</topic><topic>Vascular endothelial growth factor</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arima, Ken, MD</creatorcontrib><creatorcontrib>Katsuda, Yousuke, MD, PhD</creatorcontrib><creatorcontrib>Takeshita, Yoshiaki, MD, PhD</creatorcontrib><creatorcontrib>Saito, Yutaka, MD, PhD</creatorcontrib><creatorcontrib>Toyama, Yasuyuki, MD</creatorcontrib><creatorcontrib>Katsuki, Yoshio, MD</creatorcontrib><creatorcontrib>Ootsuka, Masanori, MD</creatorcontrib><creatorcontrib>Koiwaya, Hiroshi, MD</creatorcontrib><creatorcontrib>Sasaki, Ken-ichiro, MD, PhD</creatorcontrib><creatorcontrib>Kai, Hisashi, MD, PhD</creatorcontrib><creatorcontrib>Imaizumi, Tsutomu, MD, PhD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arima, Ken, MD</au><au>Katsuda, Yousuke, MD, PhD</au><au>Takeshita, Yoshiaki, MD, PhD</au><au>Saito, Yutaka, MD, PhD</au><au>Toyama, Yasuyuki, MD</au><au>Katsuki, Yoshio, MD</au><au>Ootsuka, Masanori, MD</au><au>Koiwaya, Hiroshi, MD</au><au>Sasaki, Ken-ichiro, MD, PhD</au><au>Kai, Hisashi, MD, PhD</au><au>Imaizumi, Tsutomu, MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Autologous Transplantation of Bone Marrow Mononuclear Cells Improved Ischemic Peripheral Neuropathy in Humans</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2010-07-13</date><risdate>2010</risdate><volume>56</volume><issue>3</issue><spage>238</spage><epage>239</epage><pages>238-239</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>[...]we examined whether autologous transplantation of BM-MNCs would improve ischemic neuropathy with critical limb ischemia in humans. 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| subjects | Angiogenesis Arterial Occlusive Diseases - complications Biological and medical sciences Bone marrow Bone Marrow Transplantation Cardiology Cardiology. Vascular system Cardiovascular Humans Internal Medicine Ischemia Medical imaging Medical sciences Middle Aged Pain Peripheral Nervous System Diseases - surgery Transplantation, Autologous Transplants & implants Vascular endothelial growth factor |
| title | Autologous Transplantation of Bone Marrow Mononuclear Cells Improved Ischemic Peripheral Neuropathy in Humans |
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