Elastometry and Clinical Results After Bipolar Radiofrequency Treatment of Skin

BACKGROUND The healing process of a novel radiofrequency bipolar system was recently shown to produce a profound increase in collagen and elastin content. OBJECTIVE To determine the relationship between subjective clinical improvement scores and changes in objective measures of mechanical skin properties. METHODS AND MATERIALS Elastometry measurements were made at baseline and 3 months after treatment. All patients received a treatment zone on the lower face. Patient assessments of results and physician ratings of wrinkle and skin laxity were collected at baseline and 3 and 6 months after treatment. Elastometry and clinical results were then compared. RESULTS Three months after treatment, elastometry measurements showed statistically significant improvement (5–12% decrease in Young's Modulus and 10–16% decrease in retraction time). The average improvement correlated to a 2.6‐year improvement in skin property. Physician scores at 3 months showed a statistically significant improvement of 1.42 grades on the Fitzpatrick scale for wrinkles and 0.66 grades on the Alexiades scale for skin laxity, increasing to 1.57 and 0.70 improvement, respectively, at 6 months. Eighty‐nine percent and 91% of patients were satisfied or very satisfied with the procedure at 3‐ and 6‐month follow‐up, respectively. CONCLUSION Elastometry data showed an average decrease in Young's Modulus and retraction time, both of which suggest that radiofrequency bipolar treatment resulted in more youthful skin. Better mechanical characteristics were consistent with improvements in wrinkles, laxity, and skin quality and appearance. Funding provided by Primaeva Medical, Inc. Drs. Willey, Kilmer, Newman, and Hantash serve on the advisory board of Primeava Medical. Drs. Berube and Renton and Mr. Krishna and Mr. McGill are employees of Primaeva Medical.