Robust preparation of novel imidazo[5,1-b][1,3,4]oxadiazoles

Robust preparation of novel imidazo[5,1-b][1,3,4]oxadiazoles

Cyclodehydration of amino acid-derived acyl hydrazide amides to the corresponding oxadiazoles was followed by a second dehydration event, smoothly furnishing the novel imidazo[5,1-b][1,3,4]oxadiazole motif .

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Veröffentlicht in:Organic & biomolecular chemistry 2009-01, Vol.7 (24), p.5063-5066
Hauptverfasser: Tran, Tuan P, Patel, Nandini, Samas, Brian, Schwarz, Jacob B
Format: Artikel
Sprache:eng
Schlagworte:
Amides - chemistry
Amino Acids - chemistry
Oxadiazoles - chemical synthesis
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Beschreibung
Zusammenfassung:Cyclodehydration of amino acid-derived acyl hydrazide amides to the corresponding oxadiazoles was followed by a second dehydration event, smoothly furnishing the novel imidazo[5,1-b][1,3,4]oxadiazole motif .
ISSN:1477-0520
1477-0539
DOI:10.1039/b916188k