Asymmetric organocatalytic formal double-arylation of azomethines for the synthesis of highly enantiomerically enriched isoindolines

Asymmetric organocatalytic formal double-arylation of azomethines for the synthesis of highly enantiomerically enriched isoindolines

Isoindoline derivatives with high enantiomeric purity (up to 98% ee) have been accessed by formal double arylation of azomethines.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2010-01, Vol.46 (8), p.1275-1277
Hauptverfasser: Wang, Chao, Chen, Xiao-Hua, Zhou, Shi-Ming, Gong, Liu-Zhu
Format: Artikel
Sprache:eng
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Zusammenfassung:Isoindoline derivatives with high enantiomeric purity (up to 98% ee) have been accessed by formal double arylation of azomethines.
ISSN:1359-7345
1364-548X
DOI:10.1039/b917246g