Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia
A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins of unusual component structure: the content of cyclosporin A (55-60%) was the same as that in the substances produced by the m...
Gespeichert in:
| Veröffentlicht in: | Antibiotiki i himioterapiâ 2009, Vol.54 (9-10), p.6-9 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | rus |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 9 |
|---|---|
| container_issue | 9-10 |
| container_start_page | 6 |
| container_title | Antibiotiki i himioterapiâ |
| container_volume | 54 |
| creator | Bibikova, M V Darkhanova, T A Spiridonova, I A Danilenko, A N Katlinskiĭ, A V |
| description | A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins of unusual component structure: the content of cyclosporin A (55-60%) was the same as that in the substances produced by the majority of the described cultures, the content of cyclosporin B was much higher (about 40%) and the content of cyclosporin C was relatively low (about 3%). An appreciable content of cyclosporin (Leu4)Cs (3%) proved to be of interest. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_733951498</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733951498</sourcerecordid><originalsourceid>FETCH-LOGICAL-p555-ba76accf1e7e9617d0b6deb93b3c6f088c7fd53ff8e385b1ad6dc92171d1aa2f3</originalsourceid><addsrcrecordid>eNo1kMtqwzAURLVoaUKaXyjadWWQdCPbWramLwhk4725eoGKbLlWDPXf1yHpaobhMAxzR7ZMgCyEUmxD9jl_M8YAOABjD2Qj2IFLIeWWmCb1Y3S_NHlqFhNTHtMUhkzHKdnZOEv1QtsUlzGZiDbMPQ2Dj3i-mJxWsyJ-Sj3NKUSa8dJ2DV7nKeA5BHwk9x5jdvub7kj7_tY2n8Xx9PHVvByLUUpZaKxKNMZzVzlV8soyXVqnFWgwpWd1bSpvJXhfO6il5mhLa5TgFbccUXjYkedr7Tr9Z3b53PUhGxcjDi7NuasAlOQHVa_k042cde9sN06hx2np_m-BP8H9YRY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733951498</pqid></control><display><type>article</type><title>Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><creator>Bibikova, M V ; Darkhanova, T A ; Spiridonova, I A ; Danilenko, A N ; Katlinskiĭ, A V</creator><creatorcontrib>Bibikova, M V ; Darkhanova, T A ; Spiridonova, I A ; Danilenko, A N ; Katlinskiĭ, A V</creatorcontrib><description>A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins of unusual component structure: the content of cyclosporin A (55-60%) was the same as that in the substances produced by the majority of the described cultures, the content of cyclosporin B was much higher (about 40%) and the content of cyclosporin C was relatively low (about 3%). An appreciable content of cyclosporin (Leu4)Cs (3%) proved to be of interest.</description><identifier>ISSN: 0235-2990</identifier><identifier>PMID: 20415255</identifier><language>rus</language><publisher>Russia (Federation)</publisher><subject>Cyclosporins - isolation & purification ; Hypocreales - chemistry ; Immunosuppressive Agents - isolation & purification ; Siberia ; Soil Microbiology</subject><ispartof>Antibiotiki i himioterapiâ, 2009, Vol.54 (9-10), p.6-9</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,4010</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20415255$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bibikova, M V</creatorcontrib><creatorcontrib>Darkhanova, T A</creatorcontrib><creatorcontrib>Spiridonova, I A</creatorcontrib><creatorcontrib>Danilenko, A N</creatorcontrib><creatorcontrib>Katlinskiĭ, A V</creatorcontrib><title>Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia</title><title>Antibiotiki i himioterapiâ</title><addtitle>Antibiot Khimioter</addtitle><description>A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins of unusual component structure: the content of cyclosporin A (55-60%) was the same as that in the substances produced by the majority of the described cultures, the content of cyclosporin B was much higher (about 40%) and the content of cyclosporin C was relatively low (about 3%). An appreciable content of cyclosporin (Leu4)Cs (3%) proved to be of interest.</description><subject>Cyclosporins - isolation & purification</subject><subject>Hypocreales - chemistry</subject><subject>Immunosuppressive Agents - isolation & purification</subject><subject>Siberia</subject><subject>Soil Microbiology</subject><issn>0235-2990</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kMtqwzAURLVoaUKaXyjadWWQdCPbWramLwhk4725eoGKbLlWDPXf1yHpaobhMAxzR7ZMgCyEUmxD9jl_M8YAOABjD2Qj2IFLIeWWmCb1Y3S_NHlqFhNTHtMUhkzHKdnZOEv1QtsUlzGZiDbMPQ2Dj3i-mJxWsyJ-Sj3NKUSa8dJ2DV7nKeA5BHwk9x5jdvub7kj7_tY2n8Xx9PHVvByLUUpZaKxKNMZzVzlV8soyXVqnFWgwpWd1bSpvJXhfO6il5mhLa5TgFbccUXjYkedr7Tr9Z3b53PUhGxcjDi7NuasAlOQHVa_k042cde9sN06hx2np_m-BP8H9YRY</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Bibikova, M V</creator><creator>Darkhanova, T A</creator><creator>Spiridonova, I A</creator><creator>Danilenko, A N</creator><creator>Katlinskiĭ, A V</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2009</creationdate><title>Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia</title><author>Bibikova, M V ; Darkhanova, T A ; Spiridonova, I A ; Danilenko, A N ; Katlinskiĭ, A V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p555-ba76accf1e7e9617d0b6deb93b3c6f088c7fd53ff8e385b1ad6dc92171d1aa2f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>rus</language><creationdate>2009</creationdate><topic>Cyclosporins - isolation & purification</topic><topic>Hypocreales - chemistry</topic><topic>Immunosuppressive Agents - isolation & purification</topic><topic>Siberia</topic><topic>Soil Microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bibikova, M V</creatorcontrib><creatorcontrib>Darkhanova, T A</creatorcontrib><creatorcontrib>Spiridonova, I A</creatorcontrib><creatorcontrib>Danilenko, A N</creatorcontrib><creatorcontrib>Katlinskiĭ, A V</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Antibiotiki i himioterapiâ</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bibikova, M V</au><au>Darkhanova, T A</au><au>Spiridonova, I A</au><au>Danilenko, A N</au><au>Katlinskiĭ, A V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia</atitle><jtitle>Antibiotiki i himioterapiâ</jtitle><addtitle>Antibiot Khimioter</addtitle><date>2009</date><risdate>2009</risdate><volume>54</volume><issue>9-10</issue><spage>6</spage><epage>9</epage><pages>6-9</pages><issn>0235-2990</issn><abstract>A micromycete culture was isolated from a soil sample of Buryatiya and identified as Tolypocladium inflatum No. 2. The culture was shown to produce a complex of cyclosporins of unusual component structure: the content of cyclosporin A (55-60%) was the same as that in the substances produced by the majority of the described cultures, the content of cyclosporin B was much higher (about 40%) and the content of cyclosporin C was relatively low (about 3%). An appreciable content of cyclosporin (Leu4)Cs (3%) proved to be of interest.</abstract><cop>Russia (Federation)</cop><pmid>20415255</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0235-2990 |
| ispartof | Antibiotiki i himioterapiâ, 2009, Vol.54 (9-10), p.6-9 |
| issn | 0235-2990 |
| language | rus |
| recordid | cdi_proquest_miscellaneous_733951498 |
| source | MEDLINE; DOAJ Directory of Open Access Journals |
| subjects | Cyclosporins - isolation & purification Hypocreales - chemistry Immunosuppressive Agents - isolation & purification Siberia Soil Microbiology |
| title | Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T17%3A05%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Complex%20of%20cyclosporins%20produced%20by%20Tolypocladium%20inflatum%20isolated%20from%20soil%20sample%20from%20Buriatiia&rft.jtitle=Antibiotiki%20i%20himioterapi%C3%A2&rft.au=Bibikova,%20M%20V&rft.date=2009&rft.volume=54&rft.issue=9-10&rft.spage=6&rft.epage=9&rft.pages=6-9&rft.issn=0235-2990&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E733951498%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=733951498&rft_id=info:pmid/20415255&rfr_iscdi=true |