Nasopharyngeal carcinoma: relationship between 18F-FDG PET-CT maximum standardized uptake value, metabolic tumour volume and total lesion glycolysis and TNM classification

PURPOSEWe aimed to evaluate the relationships between primary tumour; maximum standardized uptake value (SUVmax), metabolic tumour volume (TV) and total lesion glycolysis (TLG) and tumour-node metastases (TNM) classification in nasopharyngeal carcinoma (NPC) patients. METHODSFluorine-18 fluorodeoxyg...

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Veröffentlicht in:	Nuclear medicine communications 2010-03, Vol.31 (3), p.206-210
Hauptverfasser:	Chan, Winnie K.S, Mak, Henry K.F, Huang, Bingsheng, Yeung, David W.C, Kwong, Dora Lai-Wan, Khong, Pek-Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Carcinoma - radiotherapy Female Fluorodeoxyglucose F18 - pharmacology Glycolysis Humans Lymphatic Metastasis Male Middle Aged Nasopharyngeal Neoplasms - metabolism Nasopharyngeal Neoplasms - radiotherapy Positron-Emission Tomography - methods Retrospective Studies Tomography, X-Ray Computed - methods
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Zusammenfassung:	PURPOSEWe aimed to evaluate the relationships between primary tumour; maximum standardized uptake value (SUVmax), metabolic tumour volume (TV) and total lesion glycolysis (TLG) and tumour-node metastases (TNM) classification in nasopharyngeal carcinoma (NPC) patients. METHODSFluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography scans of 57 consecutive newly diagnosed NPC patients (age range, 15–80 years) were retrospectively reviewed. SUVmax, TV and TLG were recorded. Two-tailed Spearmanʼs correlation was used to analyse the relationships between the metabolic parameters and the TNM staging system. RESULTSPositive correlations were observed between SUVmax (P
ISSN:	0143-3636 1473-5628
DOI:	10.1097/MNM.0b013e328333e3ef