New approaches for functional genomic studies in staphylococci

Abstract Functional transcriptomics studies have resulted in interesting insights into Staphylococcus aureus diversity and pathogenicity. Here we review the principles, advantages and disadvantages of recent technical developments in the field of transcriptomics and their potential impact on S. aure...

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Veröffentlicht in:	International journal of medical microbiology 2010-02, Vol.300 (2), p.88-97
Hauptverfasser:	Beaume, Marie, Hernandez, David, Francois, Patrice, Schrenzel, Jacques
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DNA, Bacterial - analysis DNA, Bacterial - genetics DNA, Bacterial - metabolism Gene Expression Regulation, Bacterial Genetic Techniques Genetic Variation Genome, Bacterial High-throughput sequencing Humans Infectious Disease Medical Education Microarrays NanoString nCounterTM assay RNA-seq RT-PCR SAGE Staphylococcal Infections - metabolism Staphylococcal Infections - microbiology Staphylococcus aureus Staphylococcus aureus - genetics Staphylococcus aureus - metabolism Staphylococcus aureus - pathogenicity Transcriptomics Virulence
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Beschreibung
Zusammenfassung:	Abstract Functional transcriptomics studies have resulted in interesting insights into Staphylococcus aureus diversity and pathogenicity. Here we review the principles, advantages and disadvantages of recent technical developments in the field of transcriptomics and their potential impact on S. aureus research.
ISSN:	1438-4221 1618-0607
DOI:	10.1016/j.ijmm.2009.11.001