The evaluation of quinonoid compounds against Trypanosoma cruzi: Synthesis of imidazolic anthraquinones, nor-β-lapachone derivatives and β-lapachone-based 1,2,3-triazoles

In continuation to our screening program of napththoquinones with activity against bloodstream trypomastigote forms of Trypanosoma cruzi, the etiological agent of Chagas’ disease, new β-lapachone-based 1,2,3-triazoles, 3-arylamino-nor-β-lapachones, 3-alkoxy-nor-β-lapachones and imidazole anthraquino...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2010-05, Vol.18 (9), p.3224-3230
Hauptverfasser: da Silva Júnior, Eufrânio N., Guimarães, Tiago T., Menna-Barreto, Rubem F.S., Pinto, Maria do Carmo F.R., de Simone, Carlos A., Pessoa, Claudia, Cavalcanti, Bruno C., Sabino, José R., Andrade, Carlos Kleber Z., Goulart, Marilia O.F., de Castro, Solange L., Pinto, Antônio V.
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