Intracranial Metastasis from an Esophageal Gastrointestinal Stromal Tumor

We report the case of a woman with intracranial metastasis from an esophageal gastrointestinal stromal tumor (GIST) with the mutation site in the 3' end of exon 11. Frontal craniotomy was performed with complete resection of the mass, followed by postoperative stereotaxic radiotherapy (SRT). In...

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Veröffentlicht in:	Internal Medicine 2010, Vol.49(8), pp.781-785
Hauptverfasser:	Hamada, Satoshi, Itami, Atsushi, Watanabe, Go, Nakayama, Shinya, Tanaka, Eiji, Hojo, Masato, Yoshizawa, Akihiko, Hirota, Seiichi, Sakai, Yoshiharu
Format:	Artikel
Sprache:	eng
Schlagworte:	brain metastasis Brain Neoplasms - diagnosis Brain Neoplasms - genetics Brain Neoplasms - secondary Brain Neoplasms - therapy Case reports Esophageal Neoplasms - diagnosis Esophageal Neoplasms - genetics Esophageal Neoplasms - therapy Esophagus Exons Female gastrointestinal stromal tumor Gastrointestinal Stromal Tumors - diagnosis Gastrointestinal Stromal Tumors - genetics Gastrointestinal Stromal Tumors - therapy Humans imatinib Metastases Middle Aged Mutation Mutation - genetics mutation analysis Radiotherapy Tumors
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Zusammenfassung:	We report the case of a woman with intracranial metastasis from an esophageal gastrointestinal stromal tumor (GIST) with the mutation site in the 3' end of exon 11. Frontal craniotomy was performed with complete resection of the mass, followed by postoperative stereotaxic radiotherapy (SRT). Intracranial metastasis from GISTs is extremely rare; we found only seven case reports in the literature.
ISSN:	0918-2918 1349-7235 1349-7235
DOI:	10.2169/internalmedicine.49.3124