A Role for Vasopressin in the Stress-Induced Inhibition of Gonadotrophin Secretion: Studies in the Brattleboro Rat

The effects of stress on the secretion of adrenocorticotrophin, corticosterone and luteinizing hormone (LH) in rats congenially lacking hypothalamic vasopressin (Brattleboro rats) and in normal controls of the parent strain (Long Evans) have been compared in an attempt to examine the role of vasopre...

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Veröffentlicht in:Journal of neuroendocrinology 1991-08, Vol.3 (4), p.413-417
Hauptverfasser: Cover, P. O., Laycock, J. F., Gartside, I. B., Buckingham, J. C.
Format: Artikel
Sprache:eng
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Zusammenfassung:The effects of stress on the secretion of adrenocorticotrophin, corticosterone and luteinizing hormone (LH) in rats congenially lacking hypothalamic vasopressin (Brattleboro rats) and in normal controls of the parent strain (Long Evans) have been compared in an attempt to examine the role of vasopressin in the stress‐induced depression of gonadotrophin secretion. In the Long Evans rats, stress (0.6 mg/100g histamine, ip) initiated, within 5 and 20 min respectively, significant (P
ISSN:0953-8194
1365-2826
DOI:10.1111/j.1365-2826.1991.tb00296.x