Failure of reticular erythematous mucinosis to respond to cyclosporine

We describe a 48-year-old woman who had worsening psoriasis, photosensitive reticular erythematous mucinosis (REM), and acne rosacea. The psoriasis was unresponsive to etretinate, and the REM was unsuccessfully treated with hydroxychloroquine. Cyclosporine (6 mg/kg/day) successfully cleared the psor...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 1992-11, Vol.27 (5), p.825-828
Hauptverfasser:	Bulengo-Ransby, Stella M., Ellis, Charles N., Griffiths, Christopher E.M., Cantu-Gonzalez, Graciela, Dubin, Howard V., Voorhees, John J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cyclosporine - therapeutic use Female Humans Medical sciences Middle Aged Mucinoses - drug therapy Mucinoses - pathology Pharmacology. Drug treatments Photosensitivity Disorders - drug therapy Photosensitivity Disorders - pathology Psoriasis - drug therapy Rosacea - drug therapy Skin, nail, hair, dermoskeleton
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Zusammenfassung:	We describe a 48-year-old woman who had worsening psoriasis, photosensitive reticular erythematous mucinosis (REM), and acne rosacea. The psoriasis was unresponsive to etretinate, and the REM was unsuccessfully treated with hydroxychloroquine. Cyclosporine (6 mg/kg/day) successfully cleared the psoriasis in 8 weeks but did not improve the REM and acne rosacea. Possible causes for the lack of response of the REM to cyclosporine are discussed.
ISSN:	0190-9622 1097-6787
DOI:	10.1016/0190-9622(92)70257-G