Genetic comparison of HIV-1 isolates from Africa, Europe, and North America
The objective of this work was to evaluate further variability among HIV-1 isolates from Africa. A genetic typing system based on the polymerase chain reaction (PCR) was developed and used to characterize isolates from diverse locales in Africa and from North America and Europe. The results indicate...
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| Veröffentlicht in: | AIDS research and human retroviruses 1992-08, Vol.8 (8), p.1467-1469 |
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| container_title | AIDS research and human retroviruses |
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| creator | LOUWAGIE, J MCCUTCHAN, F UNGAR, B BURKE, D VAN DER GROEN, G PEETERS, M FRANSEN, K PIOT, P GERSHY-DAMET, G.-M ROELANTS, G VAN HEUVERSWYN, H EDDY, G |
| description | The objective of this work was to evaluate further variability among HIV-1 isolates from Africa. A genetic typing system based on the polymerase chain reaction (PCR) was developed and used to characterize isolates from diverse locales in Africa and from North America and Europe. The results indicate that the diversity of HIV-1 in Africa may be considerably greater than anticipated and that distantly related variants sometimes are intermixed in a single location. |
| doi_str_mv | 10.1089/aid.1992.8.1467 |
| format | Article |
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A genetic typing system based on the polymerase chain reaction (PCR) was developed and used to characterize isolates from diverse locales in Africa and from North America and Europe. The results indicate that the diversity of HIV-1 in Africa may be considerably greater than anticipated and that distantly related variants sometimes are intermixed in a single location.</description><subject>Africa</subject><subject>AIDS/HIV</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>DNA Mutational Analysis</subject><subject>DNA, Viral</subject><subject>Europe</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene Frequency</subject><subject>Genetic Variation</subject><subject>HIV-1 - genetics</subject><subject>Microbiology</subject><subject>Morphology, structure, chemical composition, physicochemical properties</subject><subject>North America</subject><subject>Polymerase Chain Reaction</subject><subject>Population</subject><subject>Virology</subject><issn>0889-2229</issn><issn>1931-8405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD1PwzAQhi0EKqUwMyF5QExN6q8k9lhVpa2oYKlYLcc9i6AkLnY68O9J1ApGptPpfe6V7kHonpKUEqlmptqnVCmWypSKvLhAY6o4TaQg2SUaEylVwhhT1-gmxk9CiGIsG6FRz-ZK8jF6WUELXWWx9c3BhCr6FnuH15v3hOJ-q00HEbvgGzx3obJmipfH4A8wxabd41cfug88b2CIbtGVM3WEu_OcoN3zcrdYJ9u31WYx3yaWZ6xLhJMOCiAZMy4vQRRGlaUhjkvmSlVQy0oiM8VKKwC4KSzvv3BSMiGtI5RP0NOp9hD81xFip5sqWqhr04I_Rl1wrojIyb8gzbnKC8V7cHYCbfAxBnD6EKrGhG9NiR40616zHjRrqQfN_cXDufpYNrD_409e-_zxnJtoTe2CaW0VfzEhiFAZ5T9Mj4QD</recordid><startdate>19920801</startdate><enddate>19920801</enddate><creator>LOUWAGIE, J</creator><creator>MCCUTCHAN, F</creator><creator>UNGAR, B</creator><creator>BURKE, D</creator><creator>VAN DER GROEN, G</creator><creator>PEETERS, M</creator><creator>FRANSEN, K</creator><creator>PIOT, P</creator><creator>GERSHY-DAMET, G.-M</creator><creator>ROELANTS, G</creator><creator>VAN HEUVERSWYN, H</creator><creator>EDDY, G</creator><general>Liebert</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19920801</creationdate><title>Genetic comparison of HIV-1 isolates from Africa, Europe, and North America</title><author>LOUWAGIE, J ; MCCUTCHAN, F ; UNGAR, B ; BURKE, D ; VAN DER GROEN, G ; PEETERS, M ; FRANSEN, K ; PIOT, P ; GERSHY-DAMET, G.-M ; ROELANTS, G ; VAN HEUVERSWYN, H ; EDDY, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-4f8fe7e052af6be47a9bba0f382fb971c2b08592bc4ee3a7c3889f88248cf013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Africa</topic><topic>AIDS/HIV</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>DNA Mutational Analysis</topic><topic>DNA, Viral</topic><topic>Europe</topic><topic>Fundamental and applied biological sciences. 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A genetic typing system based on the polymerase chain reaction (PCR) was developed and used to characterize isolates from diverse locales in Africa and from North America and Europe. The results indicate that the diversity of HIV-1 in Africa may be considerably greater than anticipated and that distantly related variants sometimes are intermixed in a single location.</abstract><cop>Larchmont, NY</cop><pub>Liebert</pub><pmid>1466983</pmid><doi>10.1089/aid.1992.8.1467</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0889-2229 |
| ispartof | AIDS research and human retroviruses, 1992-08, Vol.8 (8), p.1467-1469 |
| issn | 0889-2229 1931-8405 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73390460 |
| source | Mary Ann Liebert Online Subscription; MEDLINE |
| subjects | Africa AIDS/HIV Base Sequence Biological and medical sciences DNA Mutational Analysis DNA, Viral Europe Fundamental and applied biological sciences. Psychology Gene Frequency Genetic Variation HIV-1 - genetics Microbiology Morphology, structure, chemical composition, physicochemical properties North America Polymerase Chain Reaction Population Virology |
| title | Genetic comparison of HIV-1 isolates from Africa, Europe, and North America |
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