Genetic comparison of HIV-1 isolates from Africa, Europe, and North America

The objective of this work was to evaluate further variability among HIV-1 isolates from Africa. A genetic typing system based on the polymerase chain reaction (PCR) was developed and used to characterize isolates from diverse locales in Africa and from North America and Europe. The results indicate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	AIDS research and human retroviruses 1992-08, Vol.8 (8), p.1467-1469
Hauptverfasser:	LOUWAGIE, J, MCCUTCHAN, F, UNGAR, B, BURKE, D, VAN DER GROEN, G, PEETERS, M, FRANSEN, K, PIOT, P, GERSHY-DAMET, G.-M, ROELANTS, G, VAN HEUVERSWYN, H, EDDY, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa AIDS/HIV Base Sequence Biological and medical sciences DNA Mutational Analysis DNA, Viral Europe Fundamental and applied biological sciences. Psychology Gene Frequency Genetic Variation HIV-1 - genetics Microbiology Morphology, structure, chemical composition, physicochemical properties North America Polymerase Chain Reaction Population Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The objective of this work was to evaluate further variability among HIV-1 isolates from Africa. A genetic typing system based on the polymerase chain reaction (PCR) was developed and used to characterize isolates from diverse locales in Africa and from North America and Europe. The results indicate that the diversity of HIV-1 in Africa may be considerably greater than anticipated and that distantly related variants sometimes are intermixed in a single location.
ISSN:	0889-2229 1931-8405
DOI:	10.1089/aid.1992.8.1467