Acute bronchodilator responsiveness in subjects with and without airflow obstruction in five Latin American cities: The PLATINO study

Abstract Background Acute bronchodilator responsiveness is an area of discussion in COPD. No information exists regarding this aspect of the disease from an unselected COPD population. We assessed acute bronchodilator responsiveness and factors influencing it in subjects with and without airway obstruction in an epidemiologic sample. Methods COPD was defined by GOLD criteria (post-bronchodilator FEV1 /FVC < 0.70). In this analysis, subjects with pre-bronchodilator FEV1 /FVC