Treatment with Monoclonal Antibodies against Clostridium difficile Toxins
To the Editor: The findings by Lowy and colleagues (Jan. 21 issue) 1 demonstrate the value of fully human monoclonal antibodies in preventing the recurrence of Clostridium difficile infection. The prevalence of C. difficile infection in hospitalized patients is greatest among patients older than 85...
Gespeichert in:
Veröffentlicht in: | The New England journal of medicine 2010-04, Vol.362 (15), p.1444-1446 |
---|---|
Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | To the Editor:
The findings by Lowy and colleagues (Jan. 21 issue)
1
demonstrate the value of fully human monoclonal antibodies in preventing the recurrence of
Clostridium difficile
infection. The prevalence of
C. difficile
infection in hospitalized patients is greatest among patients older than 85 years of age,
2
and recurrent
C. difficile
infection is both more frequent and more problematic in older adults.
3
Although the oldest patient in the trial conducted by Lowy et al. was 101 years old, the mean age was 64 years. We recently reported that the natural history of
C. difficile
infection in frail, elderly patients is . . . |
---|---|
ISSN: | 0028-4793 1533-4406 |
DOI: | 10.1056/NEJMc1002213 |