Intraspecies transmission of L-type-like bovine spongiform encephalopathy detected in Japan

ABSTRACT It has been assumed that the agent causing BSE in cattle is a uniform strain (classical BSE); however, different neuropathological and molecular phenotypes of BSE (atypical BSE) have been recently reported. We demonstrated the successful transmission of L‐type‐like atypical BSE detected in...

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Veröffentlicht in:	Microbiology and immunology 2009-12, Vol.53 (12), p.704-707
Hauptverfasser:	Fukuda, Shigeo, Iwamaru, Yoshifumi, Imamura, Morikazu, Masujin, Kentarou, Shimizu, Yoshihisa, Matsuura, Yuichi, Shu, Yujing, Kurachi, Megumi, Kasai, Kazuo, Murayama, Yuichi, Onoe, Sadao, Hagiwara, Ken'ichi, Sata, Tetsutaro, Mohri, Shirou, Yokoyama, Takashi, Okada, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals atypical bovine spongiform encephalopathy Cattle Cattle Diseases - genetics Cattle Diseases - pathology Cattle Diseases - transmission Encephalopathy, Bovine Spongiform - genetics Encephalopathy, Bovine Spongiform - pathology Encephalopathy, Bovine Spongiform - transmission Infectious Disease Incubation Period Japan L-type-like Medulla Oblongata - pathology Mice Prion Diseases - genetics Prion Diseases - transmission Prions - classification Prions - pathogenicity PrPC Proteins - genetics PrPC Proteins - isolation & purification PrPC Proteins - metabolism Species Specificity transmission
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