Radiofrequency ablation as a palliative therapy option in ENT tumors: in vivo and in vitro testing
High frequency thermotherapy (HFTT) is an established palliative therapy for hepatic malignancies. An in vivo and in vitro trial examined the preconditions for the application of HFTT with liquid-cooled wet electrodes for minimally invasive palliation of head and neck tumors. HFTT was applied with n...
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Veröffentlicht in: | HNO 2010-04, Vol.58 (4), p.358-363 |
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Zusammenfassung: | High frequency thermotherapy (HFTT) is an established palliative therapy for hepatic malignancies. An in vivo and in vitro trial examined the preconditions for the application of HFTT with liquid-cooled wet electrodes for minimally invasive palliation of head and neck tumors.
HFTT was applied with needle electrodes, cooled with isotonic saline solution, and a high-frequency generator (Elektrotom HiTT 106, Berchtold, Tuttlingen) to porcine tongue and narcotized, juvenile domestic pigs to the tongue and neck, and monitored in realtime by B-mode ultrasound.
The direction of spread of the hyperthermic zone is well observed using ultrasound. Determining the direction of spread is not possible with cooled-tip electrode needles. Severe complications were not observed during the application.
RFA with liquid-cooled needle applicators is not safely applicable for the therapy of head and neck tumors. |
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ISSN: | 1433-0458 |
DOI: | 10.1007/s00106-009-2067-0 |