Liquid chromatographic determination of the known low level impurities in lovastatin bulk drug: An application of high—low chromatography
High—low chromatography in combination with gradient elution and multiple wavelength detection is a rapid and sensitive technique that can be used to assay low level impurities in lovastatin. The method is reproducible and can be applied to samples containing as little as 0.1% of any known impurity....
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Veröffentlicht in: | Talanta (Oxford) 1993-04, Vol.40 (4), p.491-494 |
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container_title | Talanta (Oxford) |
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creator | Houck, Anthony Thomas, Scott Ellison, Dean K. |
description | High—low chromatography in combination with gradient elution and multiple wavelength detection is a rapid and sensitive technique that can be used to assay low level impurities in lovastatin. The method is reproducible and can be applied to samples containing as little as 0.1% of any known impurity. |
doi_str_mv | 10.1016/0039-9140(93)80005-C |
format | Article |
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language | eng |
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source | Elsevier ScienceDirect Journals |
subjects | Analysis Biological and medical sciences General pharmacology Medical sciences Pharmacology. Drug treatments |
title | Liquid chromatographic determination of the known low level impurities in lovastatin bulk drug: An application of high—low chromatography |
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