Spectrophotometric determination of the theophylline in plasma by the apparent content curves method

Spectrophotometric determination of the theophylline in plasma by the apparent content curves method

A direct spectrophotometric procedure for the determination of theophylline in plasma is proposed. This procedure is based on the apparent content curves method and it is not necessary to know the nature and contents of interferent substances. Bias errors introduced by plasma and metabolites are avo...

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Veröffentlicht in:Talanta (Oxford) 1996-09, Vol.43 (9), p.1589-1594
Hauptverfasser: LLOBATESTELLES, M, MARINSAEZ, R, SANMARTINCIGES, M
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Apparent content curves method
Biological and medical sciences
General pharmacology
Medical sciences
Pharmacology. Drug treatments
Plasma
Spectrophotometry
Theophylline
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Zusammenfassung:A direct spectrophotometric procedure for the determination of theophylline in plasma is proposed. This procedure is based on the apparent content curves method and it is not necessary to know the nature and contents of interferent substances. Bias errors introduced by plasma and metabolites are avoided. The results obtained are in agreement with those provided by an immunofluoroassay used as a reference method.
ISSN:0039-9140
1873-3573
DOI:10.1016/0039-9140(96)01902-9