Comparative Activity of Pradofloxacin, Enrofloxacin, and Azithromycin against Bartonella henselae Isolates Collected from Cats and a Human

Using Bartonella henselae isolates from cats and a human, the activity of pradofloxacin was compared with those of enrofloxacin and azithromycin. By Etest and disc diffusion assay, pradofloxacin showed greater antimicrobial activity than did other antibiotics. We conclude that pradofloxacin may prov...

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Veröffentlicht in:	Journal of Clinical Microbiology 2010-02, Vol.48 (2), p.617-618
Hauptverfasser:	Biswas, Silpak, Maggi, Ricardo G, Papich, Mark G, Keil, Daniel, Breitschwerdt, Edward B
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiomatosis, Bacillary - microbiology Angiomatosis, Bacillary - veterinary Animals Anti-Bacterial Agents - pharmacology Azithromycin - pharmacology Bacteriology Bartonella henselae Bartonella henselae - drug effects Bartonella henselae - isolation & purification Biological and medical sciences Cat Diseases - microbiology Cat-Scratch Disease - microbiology Cats Clinical Veterinary Microbiology Fluoroquinolones - pharmacology Fundamental and applied biological sciences. Psychology Humans Microbial Sensitivity Tests Microbiology Miscellaneous
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Zusammenfassung:	Using Bartonella henselae isolates from cats and a human, the activity of pradofloxacin was compared with those of enrofloxacin and azithromycin. By Etest and disc diffusion assay, pradofloxacin showed greater antimicrobial activity than did other antibiotics. We conclude that pradofloxacin may prove useful for the treatment of B. henselae infections.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.01287-09