Impact of preoperative anemia on cardiac surgery in octogenarians

Department of Cardiac Surgery, Instituto de Ciencias del Corazón (ICICOR), University Hospital, Avda. Ramón y Cajal, 3, 47005 Valladolid, Spain *Corresponding author. Tel.: +34 983 420 000 (Ext. 191); fax: +34 983 255 305. E-mail address : ycarrascal{at}hotmail.com (Y. Carrascal). Objectives: Preoperative anemia has been related with adverse outcomes in elective valve replacement and CABG surgery. Impact of preoperative anemia on outcome in octogenarians submitted to cardiopulmonary bypass (CPB) has not yet been precisely described. Methods: We analyzed association between preoperative hemoglobin level, minimum intraoperative and immediate postoperative hematocrit (HCT), and other co-morbidities and occurrence of adverse outcomes in 227 octogenarians who underwent cardiac surgery. Results: Frequency of preoperative anemia was 41.9% (40.4% in male and 43.5% in female patients). Postoperative mortality was 13.2% (9% in non-anemic patients vs. 18.9% in anemic). 44.5% of patients suffered at least one postoperative adverse outcome (43.1% non-anemic vs. 46.3% anemic). In multivariate analysis (after adjusting independent preoperative risk factors for operative mortality and EuroSCORE) preoperative creatinin level [odds ratio (OR), 2.29; 95% confidence interval (CI), 1.06–4.98; P =0.035], immediate postoperative HCT