Neither Too Much Nor Too Little: Reactive Oxygen Species Levels Regulate Drosophila Hematopoiesis

Owing to their fast diffusion, reactive oxygen species (ROS) are important tissue signalling components. High levels of ROS are generally considered as deleterious to cells. In vivo experiments in the Drosophila hematopoietic organ now challenge this view by showing that high ROS levels are intrinsi...

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Veröffentlicht in:Journal of molecular cell biology 2010-04, Vol.2 (2), p.74-75
Hauptverfasser: Vincent, Alain, Crozatier, Michèle
Format: Artikel
Sprache:eng
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Zusammenfassung:Owing to their fast diffusion, reactive oxygen species (ROS) are important tissue signalling components. High levels of ROS are generally considered as deleterious to cells. In vivo experiments in the Drosophila hematopoietic organ now challenge this view by showing that high ROS levels are intrinsically required to prime myeloid-like progenitors to differentiate.
ISSN:1674-2788
1759-4685
DOI:10.1093/jmcb/mjp042