Male sex, single nodularity, and young age are associated with the risk of finding a papillary thyroid cancer on fine-needle aspiration cytology in a large series of patients with nodular thyroid disease

ObjectiveTo evaluate the risk of papillary thyroid carcinoma (PTC) at fine-needle aspiration (FNA) cytology in 34 120 patients.ResultsFalse positive and false negative rates of FNA cytology were 1.2 and 1.8% in comparison with the histology in 3406 nodules from 3004 patients who underwent surgery. P...

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Veröffentlicht in:	European journal of endocrinology 2010-04, Vol.162 (4), p.763-770
Hauptverfasser:	Rago, T, Fiore, E, Scutari, M, Santini, F, Di Coscio, G, Romani, R, Piaggi, P, Ugolini, C, Basolo, F, Miccoli, P, Pinchera, A, Vitti, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Factors Aged Aged, 80 and over Autoantibodies - blood Biological and medical sciences Biopsy, Fine-Needle - methods Calcitonin - blood Carcinoma, Papillary - blood Carcinoma, Papillary - diagnosis Carcinoma, Papillary - pathology Clinical Study Cytological Techniques Endocrinopathies Female Fundamental and applied biological sciences. Psychology Histocytochemistry Humans Linear Models Male Malignant tumors Medical sciences Middle Aged Non tumoral diseases. Target tissue resistance. Benign neoplasms Retrospective Studies Sex Factors Thyroid Neoplasms - blood Thyroid Neoplasms - diagnosis Thyroid Neoplasms - pathology Thyroid Nodule - blood Thyroid Nodule - diagnosis Thyroid Nodule - pathology Thyroid. Thyroid axis (diseases) Thyrotropin - blood Thyroxine - blood Triiodothyronine - blood Vertebrates: endocrinology Young Adult
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Zusammenfassung:	ObjectiveTo evaluate the risk of papillary thyroid carcinoma (PTC) at fine-needle aspiration (FNA) cytology in 34 120 patients.ResultsFalse positive and false negative rates of FNA cytology were 1.2 and 1.8% in comparison with the histology in 3406 nodules from 3004 patients who underwent surgery. PTC (901 cases) was more frequent in solitary nodule (SN; 446/13 549, 3.3%) than in multinodular goiter (MNG; 411/19 923, 2%, χ2=48.8; P
ISSN:	0804-4643 1479-683X
DOI:	10.1530/EJE-09-0895