Treg and lupus
Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms. In addition novel subsets of Treg might ar...
Gespeichert in:
| Veröffentlicht in: | Annals of the rheumatic diseases 2010-01, Vol.69 (Suppl 1), p.i65-i66 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | i66 |
|---|---|
| container_issue | Suppl 1 |
| container_start_page | i65 |
| container_title | Annals of the rheumatic diseases |
| container_volume | 69 |
| creator | Bonelli, M Smolen, J S Scheinecker, C |
| description | Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms. In addition novel subsets of Treg might arise under specific autoimmune conditions as an effort to counteract autoimmunity. Advances in our understanding of how to characterise and manipulate Treg in patients with autoimmune diseases are required in order to develop new therapeutic strategies. |
| doi_str_mv | 10.1136/ard.2009.117135 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733794815</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>733794815</sourcerecordid><originalsourceid>FETCH-LOGICAL-b397t-a4de222f8c2a3e9a4a9194db5cb2d8a63196c8eca5804ad39343ccdd432f79493</originalsourceid><addsrcrecordid>eNqF0MtLwzAcB_AgiptTr95k4EEQuuXVPI5SfI2hOKZ4C2mSyma7dskK-t-b0aHgxVP4kc_vwReAMwRHCBE21t6OMIQyVhyRdA_0EWUiwZDBfdCHEJKESsZ74CiEZSyhQOIQ9JCUMuVU9MHp3Lv3oV7ZYdk2bTgGB4UugzvZvQPwcnszz-6T6dPdQ3Y9TXIi-SbR1DqMcSEM1sRJTbVEkto8NTm2QjOCJDPCGZ0KSLUlklBijLWU4IJLKskAXHZzG1-vWxc2qloE48pSr1zdBsUJiU6gNMqLP3JZt34Vj1OIcy4YRAxHNe6U8XUI3hWq8YtK-y-FoNompWJSapuU6pKKHee7uW1eOfvrd9FEkHRgETbu8-df-w_FOOGpenzNVDaZsNnseareor_qfF4t_93-DQeFfRw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1777860162</pqid></control><display><type>article</type><title>Treg and lupus</title><source>MEDLINE</source><source>BMJ Journals - NESLi2</source><creator>Bonelli, M ; Smolen, J S ; Scheinecker, C</creator><creatorcontrib>Bonelli, M ; Smolen, J S ; Scheinecker, C</creatorcontrib><description>Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms. In addition novel subsets of Treg might arise under specific autoimmune conditions as an effort to counteract autoimmunity. Advances in our understanding of how to characterise and manipulate Treg in patients with autoimmune diseases are required in order to develop new therapeutic strategies.</description><identifier>ISSN: 0003-4967</identifier><identifier>EISSN: 1468-2060</identifier><identifier>DOI: 10.1136/ard.2009.117135</identifier><identifier>PMID: 19995748</identifier><identifier>CODEN: ARDIAO</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and European League Against Rheumatism</publisher><subject>Autoimmune diseases ; Autoimmune Diseases - immunology ; Cell growth ; Disease ; Humans ; Immunology ; Lupus ; Lupus Erythematosus, Systemic - immunology ; Lymphocytes ; T cell receptors ; T-Lymphocyte Subsets - immunology ; T-Lymphocytes, Regulatory - immunology</subject><ispartof>Annals of the rheumatic diseases, 2010-01, Vol.69 (Suppl 1), p.i65-i66</ispartof><rights>BMJ Publishing Group Ltd and European League Against Rheumatism. All rights reserved.</rights><rights>Copyright: 2010 BMJ Publishing Group Ltd and European League Against Rheumatism. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b397t-a4de222f8c2a3e9a4a9194db5cb2d8a63196c8eca5804ad39343ccdd432f79493</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://ard.bmj.com/content/69/Suppl_1/i65.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://ard.bmj.com/content/69/Suppl_1/i65.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,780,784,3196,23571,27924,27925,77600,77631</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19995748$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bonelli, M</creatorcontrib><creatorcontrib>Smolen, J S</creatorcontrib><creatorcontrib>Scheinecker, C</creatorcontrib><title>Treg and lupus</title><title>Annals of the rheumatic diseases</title><addtitle>Ann Rheum Dis</addtitle><description>Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms. In addition novel subsets of Treg might arise under specific autoimmune conditions as an effort to counteract autoimmunity. Advances in our understanding of how to characterise and manipulate Treg in patients with autoimmune diseases are required in order to develop new therapeutic strategies.</description><subject>Autoimmune diseases</subject><subject>Autoimmune Diseases - immunology</subject><subject>Cell growth</subject><subject>Disease</subject><subject>Humans</subject><subject>Immunology</subject><subject>Lupus</subject><subject>Lupus Erythematosus, Systemic - immunology</subject><subject>Lymphocytes</subject><subject>T cell receptors</subject><subject>T-Lymphocyte Subsets - immunology</subject><subject>T-Lymphocytes, Regulatory - immunology</subject><issn>0003-4967</issn><issn>1468-2060</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqF0MtLwzAcB_AgiptTr95k4EEQuuXVPI5SfI2hOKZ4C2mSyma7dskK-t-b0aHgxVP4kc_vwReAMwRHCBE21t6OMIQyVhyRdA_0EWUiwZDBfdCHEJKESsZ74CiEZSyhQOIQ9JCUMuVU9MHp3Lv3oV7ZYdk2bTgGB4UugzvZvQPwcnszz-6T6dPdQ3Y9TXIi-SbR1DqMcSEM1sRJTbVEkto8NTm2QjOCJDPCGZ0KSLUlklBijLWU4IJLKskAXHZzG1-vWxc2qloE48pSr1zdBsUJiU6gNMqLP3JZt34Vj1OIcy4YRAxHNe6U8XUI3hWq8YtK-y-FoNompWJSapuU6pKKHee7uW1eOfvrd9FEkHRgETbu8-df-w_FOOGpenzNVDaZsNnseareor_qfF4t_93-DQeFfRw</recordid><startdate>201001</startdate><enddate>201001</enddate><creator>Bonelli, M</creator><creator>Smolen, J S</creator><creator>Scheinecker, C</creator><general>BMJ Publishing Group Ltd and European League Against Rheumatism</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>201001</creationdate><title>Treg and lupus</title><author>Bonelli, M ; Smolen, J S ; Scheinecker, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b397t-a4de222f8c2a3e9a4a9194db5cb2d8a63196c8eca5804ad39343ccdd432f79493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Autoimmune diseases</topic><topic>Autoimmune Diseases - immunology</topic><topic>Cell growth</topic><topic>Disease</topic><topic>Humans</topic><topic>Immunology</topic><topic>Lupus</topic><topic>Lupus Erythematosus, Systemic - immunology</topic><topic>Lymphocytes</topic><topic>T cell receptors</topic><topic>T-Lymphocyte Subsets - immunology</topic><topic>T-Lymphocytes, Regulatory - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bonelli, M</creatorcontrib><creatorcontrib>Smolen, J S</creatorcontrib><creatorcontrib>Scheinecker, C</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the rheumatic diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bonelli, M</au><au>Smolen, J S</au><au>Scheinecker, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treg and lupus</atitle><jtitle>Annals of the rheumatic diseases</jtitle><addtitle>Ann Rheum Dis</addtitle><date>2010-01</date><risdate>2010</risdate><volume>69</volume><issue>Suppl 1</issue><spage>i65</spage><epage>i66</epage><pages>i65-i66</pages><issn>0003-4967</issn><eissn>1468-2060</eissn><coden>ARDIAO</coden><abstract>Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms. In addition novel subsets of Treg might arise under specific autoimmune conditions as an effort to counteract autoimmunity. Advances in our understanding of how to characterise and manipulate Treg in patients with autoimmune diseases are required in order to develop new therapeutic strategies.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and European League Against Rheumatism</pub><pmid>19995748</pmid><doi>10.1136/ard.2009.117135</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-4967 |
| ispartof | Annals of the rheumatic diseases, 2010-01, Vol.69 (Suppl 1), p.i65-i66 |
| issn | 0003-4967 1468-2060 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_733794815 |
| source | MEDLINE; BMJ Journals - NESLi2 |
| subjects | Autoimmune diseases Autoimmune Diseases - immunology Cell growth Disease Humans Immunology Lupus Lupus Erythematosus, Systemic - immunology Lymphocytes T cell receptors T-Lymphocyte Subsets - immunology T-Lymphocytes, Regulatory - immunology |
| title | Treg and lupus |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T04%3A42%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Treg%20and%20lupus&rft.jtitle=Annals%20of%20the%20rheumatic%20diseases&rft.au=Bonelli,%20M&rft.date=2010-01&rft.volume=69&rft.issue=Suppl%201&rft.spage=i65&rft.epage=i66&rft.pages=i65-i66&rft.issn=0003-4967&rft.eissn=1468-2060&rft.coden=ARDIAO&rft_id=info:doi/10.1136/ard.2009.117135&rft_dat=%3Cproquest_cross%3E733794815%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1777860162&rft_id=info:pmid/19995748&rfr_iscdi=true |