Mean platelet volume predicts early death in acute pulmonary embolism
BackgroundRecently, mean platelet volume (MPV) was reported to predict venous thromboembolism. Moreover, MPV correlates with platelet reactivity and indicates poor outcome in acute coronary syndromes.ObjectiveTo examine the hypothesis that in acute pulmonary embolism (APE) MPV is elevated and may pr...
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| Veröffentlicht in: | Heart (British Cardiac Society) 2010-03, Vol.96 (6), p.460-465 |
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| creator | Kostrubiec, Maciej Łabyk, Andrzej Pedowska-Włoszek, Justyna Hrynkiewicz-Szymańska, Anna Pacho, Szymon Jankowski, Krzysztof Lichodziejewska, Barbara Pruszczyk, Piotr |
| description | BackgroundRecently, mean platelet volume (MPV) was reported to predict venous thromboembolism. Moreover, MPV correlates with platelet reactivity and indicates poor outcome in acute coronary syndromes.ObjectiveTo examine the hypothesis that in acute pulmonary embolism (APE) MPV is elevated and may predict mortality.Methods and resultsThe study included consecutive 192 patients with APE, (79M/113F, 64±18 years) and 100 controls matched for age, sex and concomitant diseases. On admission blood samples were collected for MPV and troponin measurements. Although MPV did not differ between patients with APE and controls (10.0±1.2 vs 10.1±0.8 fl), it differed between low- and intermediate- or high-risk APE (9.4±1.2 fl, 10.3±1.1 fl, 10.3±1.8 fl; respectively, p |
| doi_str_mv | 10.1136/hrt.2009.180489 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_733788213</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4020818051</sourcerecordid><originalsourceid>FETCH-LOGICAL-b427t-42826afa9323c8d2a6767abce0b2c86d15d9c73f3614f1e6915223f291610ee63</originalsourceid><addsrcrecordid>eNqF0Mtr3DAQB2BRGpo07bm3YiilUPBGI9l6HMuSPiDZXraPm5DlMfFWtjeSXJr_Plq8pJBLThLMN8PMj5A3QFcAXFzchLRilOoVKFop_YycQSVUySj8fp7_vK5LQbk8JS9j3FFKK63EC3IKWgNlSp6Ry2u0Y7H3NqHHVPyd_DxgsQ_Y9i7FAm3wd0WLNt0U_VhYN6dcnf0wjTbcFTg0k-_j8IqcdNZHfH18z8mPz5fb9dfy6vuXb-tPV2VTMZnKiikmbGc1Z9ypllkhhbSNQ9owp0QLdaud5B0XUHWAQkPNGO-YBgEUUfBz8mGZuw_T7YwxmaGPDr23I05zNJJzqRQDnuW7R3I3zWHMyxmQisp8PT-oi0W5MMUYsDP70A_5MgPUHAI2OWBzCNgsAeeOt8e5czNg-98fE83g_RHY6Kzvgh1dHx8cYzXVqobsysX1MeG_h7oNf4yQXNZm83Nt5K-t4pvrrdlk_3HxzbB7cst7lp-eYA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1780702833</pqid></control><display><type>article</type><title>Mean platelet volume predicts early death in acute pulmonary embolism</title><source>MEDLINE</source><source>BMJ Journals - NESLi2</source><source>PubMed Central</source><creator>Kostrubiec, Maciej ; Łabyk, Andrzej ; Pedowska-Włoszek, Justyna ; Hrynkiewicz-Szymańska, Anna ; Pacho, Szymon ; Jankowski, Krzysztof ; Lichodziejewska, Barbara ; Pruszczyk, Piotr</creator><creatorcontrib>Kostrubiec, Maciej ; Łabyk, Andrzej ; Pedowska-Włoszek, Justyna ; Hrynkiewicz-Szymańska, Anna ; Pacho, Szymon ; Jankowski, Krzysztof ; Lichodziejewska, Barbara ; Pruszczyk, Piotr</creatorcontrib><description><![CDATA[BackgroundRecently, mean platelet volume (MPV) was reported to predict venous thromboembolism. Moreover, MPV correlates with platelet reactivity and indicates poor outcome in acute coronary syndromes.ObjectiveTo examine the hypothesis that in acute pulmonary embolism (APE) MPV is elevated and may predict mortality.Methods and resultsThe study included consecutive 192 patients with APE, (79M/113F, 64±18 years) and 100 controls matched for age, sex and concomitant diseases. On admission blood samples were collected for MPV and troponin measurements. Although MPV did not differ between patients with APE and controls (10.0±1.2 vs 10.1±0.8 fl), it differed between low- and intermediate- or high-risk APE (9.4±1.2 fl, 10.3±1.1 fl, 10.3±1.8 fl; respectively, p<0.0001). Eighteen (9%) patients with APE died during the 30-day observation. MPV was higher in non-survivors than survivors (10.7±1.4 fl vs 9.9±1.2fl, p<0.01). The areas under receiver operating characteristic curves of MPV were 0.658 (95% CI 0.587 to 0.725) for predicting 30-day mortality, and 0.712 (95% CI 0.642 to 0.775) for 7-day mortality. MPV >10.9 fl, showed sensitivity, specificity, positive predictive value and negative predictive value for death within 30 days (39%, 81%, 18%, 93%, respectively) and for 7-day mortality (54%, 82%, 18%, 96%). Multivariable analysis showed that MPV was an independent mortality predictor for 7- and 30-day all-cause mortality (HR=2.0 (95% CI 1.3 to 3.0), p<0.001)) and 1.7 (95% CI 1.2 to 2.5), p<0.01)), respectively). MPVs were higher in patients with myocardial injury than in those without troponin elevation (10.2±1.1 fl vs 9.8±1.2 fl; p=0.02). There were correlations between MPV and right ventricular diameter and right ventricular dysfunction (r=0.28, p<0.01 and r=0.19, p<0.02, respectively).ConclusionMPV is an independent predictor of early death in APE. Moreover, MPV in APE is associated with right ventricular dysfunction and myocardial injury.]]></description><identifier>ISSN: 1355-6037</identifier><identifier>EISSN: 1468-201X</identifier><identifier>DOI: 10.1136/hrt.2009.180489</identifier><identifier>PMID: 19910287</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><subject>Acute coronary syndromes ; Acute Disease ; Adult ; Aged ; Anticoagulants ; Atherosclerosis ; Biological and medical sciences ; Blood platelets ; Blood Platelets - pathology ; Cardiology. Vascular system ; Embolisms ; Female ; Heart attacks ; Humans ; Laboratories ; Male ; Mean platelet volume ; Medical sciences ; Middle Aged ; Molecular weight ; Mortality ; Pathogenesis ; Platelet Activation ; platelets ; Pneumology ; Prognosis ; Pulmonary arteries ; pulmonary embolism ; Pulmonary Embolism - blood ; Pulmonary Embolism - complications ; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases ; risk satisfaction ; Studies ; Survival Analysis ; Thromboembolism ; Thromboembolism - blood ; Thromboembolism - complications ; Troponin - blood ; Variance analysis ; Ventricular Dysfunction, Right - blood ; Ventricular Dysfunction, Right - etiology</subject><ispartof>Heart (British Cardiac Society), 2010-03, Vol.96 (6), p.460-465</ispartof><rights>2009, Published by the BMJ Publishing Group Limited For permission to use, (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright: 2009 (c) 2009, Published by the BMJ Publishing Group Limited For permission to use, (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b427t-42826afa9323c8d2a6767abce0b2c86d15d9c73f3614f1e6915223f291610ee63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://heart.bmj.com/content/96/6/460.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://heart.bmj.com/content/96/6/460.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,780,784,3196,23571,27924,27925,77600,77631</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22509851$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19910287$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kostrubiec, Maciej</creatorcontrib><creatorcontrib>Łabyk, Andrzej</creatorcontrib><creatorcontrib>Pedowska-Włoszek, Justyna</creatorcontrib><creatorcontrib>Hrynkiewicz-Szymańska, Anna</creatorcontrib><creatorcontrib>Pacho, Szymon</creatorcontrib><creatorcontrib>Jankowski, Krzysztof</creatorcontrib><creatorcontrib>Lichodziejewska, Barbara</creatorcontrib><creatorcontrib>Pruszczyk, Piotr</creatorcontrib><title>Mean platelet volume predicts early death in acute pulmonary embolism</title><title>Heart (British Cardiac Society)</title><addtitle>Heart</addtitle><description><![CDATA[BackgroundRecently, mean platelet volume (MPV) was reported to predict venous thromboembolism. Moreover, MPV correlates with platelet reactivity and indicates poor outcome in acute coronary syndromes.ObjectiveTo examine the hypothesis that in acute pulmonary embolism (APE) MPV is elevated and may predict mortality.Methods and resultsThe study included consecutive 192 patients with APE, (79M/113F, 64±18 years) and 100 controls matched for age, sex and concomitant diseases. On admission blood samples were collected for MPV and troponin measurements. Although MPV did not differ between patients with APE and controls (10.0±1.2 vs 10.1±0.8 fl), it differed between low- and intermediate- or high-risk APE (9.4±1.2 fl, 10.3±1.1 fl, 10.3±1.8 fl; respectively, p<0.0001). Eighteen (9%) patients with APE died during the 30-day observation. MPV was higher in non-survivors than survivors (10.7±1.4 fl vs 9.9±1.2fl, p<0.01). The areas under receiver operating characteristic curves of MPV were 0.658 (95% CI 0.587 to 0.725) for predicting 30-day mortality, and 0.712 (95% CI 0.642 to 0.775) for 7-day mortality. MPV >10.9 fl, showed sensitivity, specificity, positive predictive value and negative predictive value for death within 30 days (39%, 81%, 18%, 93%, respectively) and for 7-day mortality (54%, 82%, 18%, 96%). Multivariable analysis showed that MPV was an independent mortality predictor for 7- and 30-day all-cause mortality (HR=2.0 (95% CI 1.3 to 3.0), p<0.001)) and 1.7 (95% CI 1.2 to 2.5), p<0.01)), respectively). MPVs were higher in patients with myocardial injury than in those without troponin elevation (10.2±1.1 fl vs 9.8±1.2 fl; p=0.02). There were correlations between MPV and right ventricular diameter and right ventricular dysfunction (r=0.28, p<0.01 and r=0.19, p<0.02, respectively).ConclusionMPV is an independent predictor of early death in APE. Moreover, MPV in APE is associated with right ventricular dysfunction and myocardial injury.]]></description><subject>Acute coronary syndromes</subject><subject>Acute Disease</subject><subject>Adult</subject><subject>Aged</subject><subject>Anticoagulants</subject><subject>Atherosclerosis</subject><subject>Biological and medical sciences</subject><subject>Blood platelets</subject><subject>Blood Platelets - pathology</subject><subject>Cardiology. Vascular system</subject><subject>Embolisms</subject><subject>Female</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Laboratories</subject><subject>Male</subject><subject>Mean platelet volume</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Molecular weight</subject><subject>Mortality</subject><subject>Pathogenesis</subject><subject>Platelet Activation</subject><subject>platelets</subject><subject>Pneumology</subject><subject>Prognosis</subject><subject>Pulmonary arteries</subject><subject>pulmonary embolism</subject><subject>Pulmonary Embolism - blood</subject><subject>Pulmonary Embolism - complications</subject><subject>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</subject><subject>risk satisfaction</subject><subject>Studies</subject><subject>Survival Analysis</subject><subject>Thromboembolism</subject><subject>Thromboembolism - blood</subject><subject>Thromboembolism - complications</subject><subject>Troponin - blood</subject><subject>Variance analysis</subject><subject>Ventricular Dysfunction, Right - blood</subject><subject>Ventricular Dysfunction, Right - etiology</subject><issn>1355-6037</issn><issn>1468-201X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqF0Mtr3DAQB2BRGpo07bm3YiilUPBGI9l6HMuSPiDZXraPm5DlMfFWtjeSXJr_Plq8pJBLThLMN8PMj5A3QFcAXFzchLRilOoVKFop_YycQSVUySj8fp7_vK5LQbk8JS9j3FFKK63EC3IKWgNlSp6Ry2u0Y7H3NqHHVPyd_DxgsQ_Y9i7FAm3wd0WLNt0U_VhYN6dcnf0wjTbcFTg0k-_j8IqcdNZHfH18z8mPz5fb9dfy6vuXb-tPV2VTMZnKiikmbGc1Z9ypllkhhbSNQ9owp0QLdaud5B0XUHWAQkPNGO-YBgEUUfBz8mGZuw_T7YwxmaGPDr23I05zNJJzqRQDnuW7R3I3zWHMyxmQisp8PT-oi0W5MMUYsDP70A_5MgPUHAI2OWBzCNgsAeeOt8e5czNg-98fE83g_RHY6Kzvgh1dHx8cYzXVqobsysX1MeG_h7oNf4yQXNZm83Nt5K-t4pvrrdlk_3HxzbB7cst7lp-eYA</recordid><startdate>20100301</startdate><enddate>20100301</enddate><creator>Kostrubiec, Maciej</creator><creator>Łabyk, Andrzej</creator><creator>Pedowska-Włoszek, Justyna</creator><creator>Hrynkiewicz-Szymańska, Anna</creator><creator>Pacho, Szymon</creator><creator>Jankowski, Krzysztof</creator><creator>Lichodziejewska, Barbara</creator><creator>Pruszczyk, Piotr</creator><general>BMJ Publishing Group Ltd and British Cardiovascular Society</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20100301</creationdate><title>Mean platelet volume predicts early death in acute pulmonary embolism</title><author>Kostrubiec, Maciej ; Łabyk, Andrzej ; Pedowska-Włoszek, Justyna ; Hrynkiewicz-Szymańska, Anna ; Pacho, Szymon ; Jankowski, Krzysztof ; Lichodziejewska, Barbara ; Pruszczyk, Piotr</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b427t-42826afa9323c8d2a6767abce0b2c86d15d9c73f3614f1e6915223f291610ee63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Acute coronary syndromes</topic><topic>Acute Disease</topic><topic>Adult</topic><topic>Aged</topic><topic>Anticoagulants</topic><topic>Atherosclerosis</topic><topic>Biological and medical sciences</topic><topic>Blood platelets</topic><topic>Blood Platelets - pathology</topic><topic>Cardiology. Vascular system</topic><topic>Embolisms</topic><topic>Female</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Laboratories</topic><topic>Male</topic><topic>Mean platelet volume</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Molecular weight</topic><topic>Mortality</topic><topic>Pathogenesis</topic><topic>Platelet Activation</topic><topic>platelets</topic><topic>Pneumology</topic><topic>Prognosis</topic><topic>Pulmonary arteries</topic><topic>pulmonary embolism</topic><topic>Pulmonary Embolism - blood</topic><topic>Pulmonary Embolism - complications</topic><topic>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</topic><topic>risk satisfaction</topic><topic>Studies</topic><topic>Survival Analysis</topic><topic>Thromboembolism</topic><topic>Thromboembolism - blood</topic><topic>Thromboembolism - complications</topic><topic>Troponin - blood</topic><topic>Variance analysis</topic><topic>Ventricular Dysfunction, Right - blood</topic><topic>Ventricular Dysfunction, Right - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kostrubiec, Maciej</creatorcontrib><creatorcontrib>Łabyk, Andrzej</creatorcontrib><creatorcontrib>Pedowska-Włoszek, Justyna</creatorcontrib><creatorcontrib>Hrynkiewicz-Szymańska, Anna</creatorcontrib><creatorcontrib>Pacho, Szymon</creatorcontrib><creatorcontrib>Jankowski, Krzysztof</creatorcontrib><creatorcontrib>Lichodziejewska, Barbara</creatorcontrib><creatorcontrib>Pruszczyk, Piotr</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Heart (British Cardiac Society)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kostrubiec, Maciej</au><au>Łabyk, Andrzej</au><au>Pedowska-Włoszek, Justyna</au><au>Hrynkiewicz-Szymańska, Anna</au><au>Pacho, Szymon</au><au>Jankowski, Krzysztof</au><au>Lichodziejewska, Barbara</au><au>Pruszczyk, Piotr</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mean platelet volume predicts early death in acute pulmonary embolism</atitle><jtitle>Heart (British Cardiac Society)</jtitle><addtitle>Heart</addtitle><date>2010-03-01</date><risdate>2010</risdate><volume>96</volume><issue>6</issue><spage>460</spage><epage>465</epage><pages>460-465</pages><issn>1355-6037</issn><eissn>1468-201X</eissn><abstract><![CDATA[BackgroundRecently, mean platelet volume (MPV) was reported to predict venous thromboembolism. Moreover, MPV correlates with platelet reactivity and indicates poor outcome in acute coronary syndromes.ObjectiveTo examine the hypothesis that in acute pulmonary embolism (APE) MPV is elevated and may predict mortality.Methods and resultsThe study included consecutive 192 patients with APE, (79M/113F, 64±18 years) and 100 controls matched for age, sex and concomitant diseases. On admission blood samples were collected for MPV and troponin measurements. Although MPV did not differ between patients with APE and controls (10.0±1.2 vs 10.1±0.8 fl), it differed between low- and intermediate- or high-risk APE (9.4±1.2 fl, 10.3±1.1 fl, 10.3±1.8 fl; respectively, p<0.0001). Eighteen (9%) patients with APE died during the 30-day observation. MPV was higher in non-survivors than survivors (10.7±1.4 fl vs 9.9±1.2fl, p<0.01). The areas under receiver operating characteristic curves of MPV were 0.658 (95% CI 0.587 to 0.725) for predicting 30-day mortality, and 0.712 (95% CI 0.642 to 0.775) for 7-day mortality. MPV >10.9 fl, showed sensitivity, specificity, positive predictive value and negative predictive value for death within 30 days (39%, 81%, 18%, 93%, respectively) and for 7-day mortality (54%, 82%, 18%, 96%). Multivariable analysis showed that MPV was an independent mortality predictor for 7- and 30-day all-cause mortality (HR=2.0 (95% CI 1.3 to 3.0), p<0.001)) and 1.7 (95% CI 1.2 to 2.5), p<0.01)), respectively). MPVs were higher in patients with myocardial injury than in those without troponin elevation (10.2±1.1 fl vs 9.8±1.2 fl; p=0.02). There were correlations between MPV and right ventricular diameter and right ventricular dysfunction (r=0.28, p<0.01 and r=0.19, p<0.02, respectively).ConclusionMPV is an independent predictor of early death in APE. Moreover, MPV in APE is associated with right ventricular dysfunction and myocardial injury.]]></abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Cardiovascular Society</pub><pmid>19910287</pmid><doi>10.1136/hrt.2009.180489</doi><tpages>6</tpages></addata></record> |
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| subjects | Acute coronary syndromes Acute Disease Adult Aged Anticoagulants Atherosclerosis Biological and medical sciences Blood platelets Blood Platelets - pathology Cardiology. Vascular system Embolisms Female Heart attacks Humans Laboratories Male Mean platelet volume Medical sciences Middle Aged Molecular weight Mortality Pathogenesis Platelet Activation platelets Pneumology Prognosis Pulmonary arteries pulmonary embolism Pulmonary Embolism - blood Pulmonary Embolism - complications Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases risk satisfaction Studies Survival Analysis Thromboembolism Thromboembolism - blood Thromboembolism - complications Troponin - blood Variance analysis Ventricular Dysfunction, Right - blood Ventricular Dysfunction, Right - etiology |
| title | Mean platelet volume predicts early death in acute pulmonary embolism |
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