Rapidly repeated intravenous boluses of salbutamol for acute severe asthma

Summary We describe the use of intravenous boluses of salbutamol given rapidly (over 1–2 min) in children (5 µg.kg−1) and young adults (250 µg) with acute severe asthma who were not improving with doses of nebulised salbutamol. Intravenous boluses were repeated within a short time until improvement...

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Veröffentlicht in:	Anaesthesia 2003-07, Vol.58 (7), p.680-683
Hauptverfasser:	Sellers, W. F. S., Messahel, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute severe Adolescent Adrenergic beta-Agonists - administration & dosage Adrenergic beta-Agonists - therapeutic use Albuterol - administration & dosage Albuterol - therapeutic use Asthma Asthma - drug therapy Biological and medical sciences Bronchodilator Agents - administration & dosage Bronchodilator Agents - therapeutic use Child Child, Preschool Drug Administration Schedule Female Humans Infant Infusions, Intravenous intravenous Male Medical sciences Pharmacology. Drug treatments Respiratory system Salbutamol
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Beschreibung
Zusammenfassung:	Summary We describe the use of intravenous boluses of salbutamol given rapidly (over 1–2 min) in children (5 µg.kg−1) and young adults (250 µg) with acute severe asthma who were not improving with doses of nebulised salbutamol. Intravenous boluses were repeated within a short time until improvement was seen. Two of the seven patients required tracheal intubation and ventilation.
ISSN:	0003-2409 1365-2044
DOI:	10.1046/j.1365-2044.2003.03092.x