Toxicity and Influence of Streptomycin in Breeding of Mice
Summary No toxic effects were observed in albino mice fed streptomycin at daily levels of 1000, 400, 200, 100, and 50 μg for periods of one to 6 months. These levels had no significant influence on percentage fertility, litter size, number of young mice weaned, and general condition of the animals....
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1946-11, Vol.63 (2), p.451-453 |
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| container_end_page | 453 |
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| container_issue | 2 |
| container_start_page | 451 |
| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 63 |
| creator | Slanetz, Charles A. |
| description | Summary
No toxic effects were observed in albino mice fed streptomycin at daily levels of 1000, 400, 200, 100, and 50 μg for periods of one to 6 months. These levels had no significant influence on percentage fertility, litter size, number of young mice weaned, and general condition of the animals. Although no influence was evident at the various levels of streptomycin in the weight gains of first litters of mice, a greater increase in weight occurred in second litters at higher levels compared to second litters of the control and 50 μg groups. |
| doi_str_mv | 10.3181/00379727-63-15632 |
| format | Article |
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No toxic effects were observed in albino mice fed streptomycin at daily levels of 1000, 400, 200, 100, and 50 μg for periods of one to 6 months. These levels had no significant influence on percentage fertility, litter size, number of young mice weaned, and general condition of the animals. Although no influence was evident at the various levels of streptomycin in the weight gains of first litters of mice, a greater increase in weight occurred in second litters at higher levels compared to second litters of the control and 50 μg groups.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-63-15632</identifier><identifier>PMID: 20277781</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Breeding ; Mice ; Old Medline ; Reproduction ; Streptomycin - toxicity</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1946-11, Vol.63 (2), p.451-453</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20277781$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Slanetz, Charles A.</creatorcontrib><title>Toxicity and Influence of Streptomycin in Breeding of Mice</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
No toxic effects were observed in albino mice fed streptomycin at daily levels of 1000, 400, 200, 100, and 50 μg for periods of one to 6 months. These levels had no significant influence on percentage fertility, litter size, number of young mice weaned, and general condition of the animals. Although no influence was evident at the various levels of streptomycin in the weight gains of first litters of mice, a greater increase in weight occurred in second litters at higher levels compared to second litters of the control and 50 μg groups.</description><subject>Animals</subject><subject>Breeding</subject><subject>Mice</subject><subject>Old Medline</subject><subject>Reproduction</subject><subject>Streptomycin - toxicity</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1946</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtPwzAQhC0EoqXwA7ig3Dil-FGvY25Q8ahUxIFytlJnU6VKnGInEvn3JLTliLTSHuab0e4Qcs3oVLCE3VEqlFZcxSBiJkHwEzJmUshYgNanZDzo8QCMyEUIW0qZVBzOyYhTrpRK2Jjcr-rvwhZNF6UuixYuL1t0FqM6jz4aj7umrjpbuKifR4-YFW4zaG-FxUtylqdlwKvDnpDP56fV_DVevr8s5g_L2HLNmtgyOtyRSkjsmlvGQcJMotYCueaSCo0Imq0zpCgl0lmeYcIBk0yAAGrFhNzuc3e-_moxNKYqgsWyTB3WbTBKCAVKA_Qk25PW1yF4zM3OF1XqO8OoGRozx8YMCPPbWO-5OaS36wqzP8exoh6Y7oGQbtBs69a7_tt_En8AVTRxqA</recordid><startdate>194611</startdate><enddate>194611</enddate><creator>Slanetz, Charles A.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>194611</creationdate><title>Toxicity and Influence of Streptomycin in Breeding of Mice</title><author>Slanetz, Charles A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c291t-c100037a568cb2c1265645e993e2925039ee691bde0e55e04fde826e8d36360c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1946</creationdate><topic>Animals</topic><topic>Breeding</topic><topic>Mice</topic><topic>Old Medline</topic><topic>Reproduction</topic><topic>Streptomycin - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Slanetz, Charles A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Slanetz, Charles A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Toxicity and Influence of Streptomycin in Breeding of Mice</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1946-11</date><risdate>1946</risdate><volume>63</volume><issue>2</issue><spage>451</spage><epage>453</epage><pages>451-453</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
No toxic effects were observed in albino mice fed streptomycin at daily levels of 1000, 400, 200, 100, and 50 μg for periods of one to 6 months. These levels had no significant influence on percentage fertility, litter size, number of young mice weaned, and general condition of the animals. Although no influence was evident at the various levels of streptomycin in the weight gains of first litters of mice, a greater increase in weight occurred in second litters at higher levels compared to second litters of the control and 50 μg groups.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>20277781</pmid><doi>10.3181/00379727-63-15632</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1946-11, Vol.63 (2), p.451-453 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_733767966 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Breeding Mice Old Medline Reproduction Streptomycin - toxicity |
| title | Toxicity and Influence of Streptomycin in Breeding of Mice |
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