Successful treatment with recombinant factor VIIa for intractable bleeding at pelvic surgery

Postoperative bleeding may be complicated by failure to identify the site of bleeding, multiple bleeding points, and persistent hemorrhage despite surgical intervention. Activated recombinant factor VII was used successfully in a patient with life-threatening postsurgical bleeding after resection of two large extraperitoneal pelvic sarcomas. In severe hemorrhage, hemostasis can be achieved with activated recombinant factor VII.