Prevention of fibrinolytic shut-down after major surgery by intramuscular stanozolol

Prevention of fibrinolytic shut-down after major surgery by intramuscular stanozolol

The effects of a single pre-operative intramuscular injection of the anabolic steroid stanozolol (Stromba, 50 mg) on fibrinolysis and blood viscosity were evaluated in 14 patients at high risk of post-operative deep venous thrombosis. A control group of 13 high risk patients was also studied. The me...

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Veröffentlicht in:Thrombosis research 1983-08, Vol.31 (3), p.451-459
Hauptverfasser: Blamey, S.L., McArdle, B.M., Burns, P., Lowe, G.D.O., Forbes, C.D., Carter, D.C., Prentice, C.R.M.
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen - surgery
Adult
Aged
Aged, 80 and over
Anabolic Agents - administration & dosage
Anabolic Agents - adverse effects
Androgens - administration & dosage
Androgens - adverse effects
Biomarkers - blood
Blood Viscosity - drug effects
Case-Control Studies
Elective Surgical Procedures
Female
Fibrinogen - metabolism
fibrinolysis
Fibrinolysis - drug effects
Humans
Injections, Intramuscular
Liver Function Tests
Male
Middle Aged
Plasminogen - metabolism
Plasminogen Activators - blood
Postoperative Complications - blood
Postoperative Complications - etiology
Postoperative Complications - prevention & control
Preoperative Care
stanozolol
Stanozolol - administration & dosage
Stanozolol - adverse effects
surgery
Time Factors
Venous Thrombosis - blood
Venous Thrombosis - etiology
Venous Thrombosis - prevention & control
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Zusammenfassung:The effects of a single pre-operative intramuscular injection of the anabolic steroid stanozolol (Stromba, 50 mg) on fibrinolysis and blood viscosity were evaluated in 14 patients at high risk of post-operative deep venous thrombosis. A control group of 13 high risk patients was also studied. The mean level of plasma plasminogen activator activity decreased significantly (p
ISSN:0049-3848
1879-2472
DOI:10.1016/0049-3848(83)90409-7