Adverse drug reactions in an Iranian department of adult infectious diseases

Adverse drug reactions in an Iranian department of adult infectious diseases

This study aimed to assess the frequency and severity of adverse drug reactions (ADRs) (WHO definition) in hospitalized adult patients in an infectious diseases referral ward in Tehran. Of 281 patients evaluated over 6 months, a total of 170 suspected ADRs were reported among 101 patients (35.9%). T...

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Veröffentlicht in:Eastern Mediterranean health journal 2009-11, Vol.15 (6), p.1351-1357
Hauptverfasser: Kourorian, Z, Fattahi, F, Pourpak, Z, Rasoolinejad, M, Gholami, K
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Analysis of Variance
Anti-Infective Agents - adverse effects
Chi-Square Distribution
Communicable Diseases - complications
Communicable Diseases - drug therapy
Cross-Sectional Studies
Drug Monitoring
Drug Prescriptions
Drug-Related Side Effects and Adverse Reactions - chemically induced
Drug-Related Side Effects and Adverse Reactions - epidemiology
Drug-Related Side Effects and Adverse Reactions - prevention & control
Female
Gastrointestinal Diseases - chemically induced
Gastrointestinal Diseases - epidemiology
HIV Infections - complications
Hospitals, Public
Hospitals, Teaching
Humans
Inpatients - statistics & numerical data
Iran - epidemiology
Male
Middle Aged
Patient Selection
Risk Factors
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Zusammenfassung:This study aimed to assess the frequency and severity of adverse drug reactions (ADRs) (WHO definition) in hospitalized adult patients in an infectious diseases referral ward in Tehran. Of 281 patients evaluated over 6 months, a total of 170 suspected ADRs were reported among 101 patients (35.9%). The most commonly affected organ system was gastrointestinal (47.5%), and the most common class of drugs responsible was anti-infectives (93.1%). ADRs were high among HIV-positive patients (82.9%), mainly due to anti-tuberculosis drugs. Attention to appropriate prescription of drugs is required with more careful clinical and laboratory monitoring of patients.
ISSN:1020-3397