The Level of Serum Granulocyte Colony-Stimulating Factor in Cancer Patients with Leukocytosis

The Level of Serum Granulocyte Colony-Stimulating Factor in Cancer Patients with Leukocytosis

The level of serum granulocyte colony-stimulating factor (G-CSF) obtained from patients with leukocytosis (>10, 000/μl) between May 1989 and April 1991 was measured by enzyme immunoassay. Studied were 18 patients with malignant neoplasms (median age, 64 years) and 14 patients with hematologic dis...

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Veröffentlicht in:Internal Medicine 1992, Vol.31(7), pp.861-865
Hauptverfasser: SHIMASAKI, Akemi KUBO, HIRATA, Kyoji, KAWAMURA, Tetsuji, KUNIBE, Nobuya, HIRAI, Kenzo, YOSHIMOTO, Kenrou, HASHIMOTO, Hisako, NAKAHARA, Yasuharu, MOCHIZUKI, Yoshirou
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Alkaline Phosphatase - blood
Female
Granulocyte Colony-Stimulating Factor - blood
Humans
hypercalcemia
Hypercalcemia - blood
Hypercalcemia - complications
Leukocyte Count
Leukocytosis - blood
Leukocytosis - etiology
lung cancer
Lung Neoplasms - blood
Lung Neoplasms - complications
Male
Middle Aged
NAP
Neoplasms - blood
Neoplasms - complications
Neutrophils - enzymology
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Zusammenfassung:The level of serum granulocyte colony-stimulating factor (G-CSF) obtained from patients with leukocytosis (>10, 000/μl) between May 1989 and April 1991 was measured by enzyme immunoassay. Studied were 18 patients with malignant neoplasms (median age, 64 years) and 14 patients with hematologic disease (median age, 59 years). Increased serum G-CSF values ranging from 70 to 374pg/ml were noted in 7 of 15 lung cancer cases, a case of malignant thymoma and a blastic crisis of chronic myelogenous leukemia. The rest of the cases showed a normal value (
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.31.861