Sequence of bovine interleukin 7

We report the cloning and the sequencing of a cDNA coding for the mature bovine interleukin 7 (IL-7). The clone was isolated from a bovine leukemia virus (BLV)-induced B cell-lymphosarcoma cDNA library. The 5′ non-coding sequence and the sequence of the signal peptide were obtained from a clone isol...

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Veröffentlicht in:	DNA sequence 1992, Vol.3 (1), p.55-59
Hauptverfasser:	Cludts, I, Droogmans, L, Cleuter, Y, Kettmann, R, Burny, A
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Amino Acid Sequence amino acid sequences Animals Base Sequence bovine leukemia virus Cattle cDNA Cloning, Molecular complementary DNA cytokine DNA Enzootic Bovine Leukosis - genetics genbank/x64540 Humans interleukin Interleukin-7 - genetics interleukins Leukemia Virus, Bovine - metabolism Molecular Sequence Data nucleotide sequences Protein Sorting Signals - genetics Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid
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Beschreibung
Zusammenfassung:	We report the cloning and the sequencing of a cDNA coding for the mature bovine interleukin 7 (IL-7). The clone was isolated from a bovine leukemia virus (BLV)-induced B cell-lymphosarcoma cDNA library. The 5′ non-coding sequence and the sequence of the signal peptide were obtained from a clone isolated from a bovine genomic library. The entire bovine IL-7 protein is 176 amino acids long and shows 75 and 65% homology to published sequences of human and murine IL-7, respectively.
ISSN:	1042-5179 1029-2365
DOI:	10.3109/10425179209039696