Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

Ratiometric fluorescent probes based on boron dipyrromethene (BODIPY) were developed based on a novel design strategy, in which a change of the electron-withdrawing character of the 2,6-substituents resulting from reaction with a target molecule generates a fluorescence wavelength change.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2009-01 (45), p.7015-7017
Hauptverfasser: Komatsu, Toru, Urano, Yasuteru, Fujikawa, Yuuta, Kobayashi, Tomonori, Kojima, Hirotatsu, Terai, Takuya, Hanaoka, Kenjiro, Nagano, Tetsuo
Format: Artikel
Sprache:eng
Schlagworte:
Boron Compounds - chemistry
Fluorescent Dyes - chemistry
HeLa Cells
Humans
Spectrometry, Fluorescence
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Zusammenfassung:Ratiometric fluorescent probes based on boron dipyrromethene (BODIPY) were developed based on a novel design strategy, in which a change of the electron-withdrawing character of the 2,6-substituents resulting from reaction with a target molecule generates a fluorescence wavelength change.
ISSN:1359-7345
1364-548X
DOI:10.1039/b917209b