Impregnated copper on magnetite: an efficient and green catalyst for the multicomponent preparation of propargylamines under solvent free conditions

Impregnated copper on magnetite is a versatile, inexpensive and simple catalyst for the selective multicomponent reaction of terminal alkynes, aldehydes and secondary amines to give the corresponding propargylamines with excellent yields. The catalyst can be easily recovered and reused by using a si...

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Veröffentlicht in:Organic & biomolecular chemistry 2010-01, Vol.8 (1), p.43-46
Hauptverfasser: Aliaga, María J, Ramón, Diego J, Yus, Miguel
Format: Artikel
Sprache:eng
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Zusammenfassung:Impregnated copper on magnetite is a versatile, inexpensive and simple catalyst for the selective multicomponent reaction of terminal alkynes, aldehydes and secondary amines to give the corresponding propargylamines with excellent yields. The catalyst can be easily recovered and reused by using a simple magnet. The process could be repeated up to ten times without losing its activity.
ISSN:1477-0520
1477-0539
DOI:10.1039/b917923b